Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR.

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Title: Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR.
Authors: Park SJ; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kim S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kwon H; College of Pharmacy, Korea University, Sejong, Republic of Korea., Choi J; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kim JK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Jung I; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lim SW; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kim YR; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Yang AY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lee B; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lee H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Park SE; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lee S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Shin M; College of Pharmacy, Korea University, Sejong, Republic of Korea., Park BB; College of Pharmacy, Korea University, Sejong, Republic of Korea., Kim Y; College of Pharmacy, Korea University, Sejong, Republic of Korea., Lee J; Department of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, College of Medicine, Incheon, Republic of Korea., Oh BC; Department of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, College of Medicine, Incheon, Republic of Korea., Deredge D; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA., Wintrode PL; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA., Kim MY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Byun Y; College of Pharmacy, Korea University, Sejong, Republic of Korea; Interdisciplinary Major Program in Innovative Pharmaceutical Sciences, Korea University, Sejong, Republic of Korea. Electronic address: yjbyun1@korea.ac.kr., Kim S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea; KAIST Institute for the BioCentury, KAIST, Daejeon, Republic of Korea; KAIST Stem Cell Center, KAIST, Daejeon, Republic of Korea. Electronic address: seyunkim@kaist.ac.kr.
Source: Cell chemical biology [Cell Chem Biol] 2026 May 21; Vol. 33 (5), pp. 637-648.e10. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2451-9448
DOI:10.1016/j.chembiol.2026.04.004