Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR.

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Title: Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR.
Authors: Park SJ; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kim S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kwon H; College of Pharmacy, Korea University, Sejong, Republic of Korea., Choi J; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kim JK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Jung I; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lim SW; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Kim YR; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Yang AY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lee B; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lee H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Park SE; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Lee S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Shin M; College of Pharmacy, Korea University, Sejong, Republic of Korea., Park BB; College of Pharmacy, Korea University, Sejong, Republic of Korea., Kim Y; College of Pharmacy, Korea University, Sejong, Republic of Korea., Lee J; Department of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, College of Medicine, Incheon, Republic of Korea., Oh BC; Department of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, College of Medicine, Incheon, Republic of Korea., Deredge D; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA., Wintrode PL; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA., Kim MY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea., Byun Y; College of Pharmacy, Korea University, Sejong, Republic of Korea; Interdisciplinary Major Program in Innovative Pharmaceutical Sciences, Korea University, Sejong, Republic of Korea. Electronic address: yjbyun1@korea.ac.kr., Kim S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea; KAIST Institute for the BioCentury, KAIST, Daejeon, Republic of Korea; KAIST Stem Cell Center, KAIST, Daejeon, Republic of Korea. Electronic address: seyunkim@kaist.ac.kr.
Source: Cell chemical biology [Cell Chem Biol] 2026 May 21; Vol. 33 (5), pp. 637-648.e10. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
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  Data: Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR.
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  Data: <searchLink fieldCode="AU" term="%22Park+SJ%22">Park SJ</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+H%22">Kwon H</searchLink>; College of Pharmacy, Korea University, Sejong, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+J%22">Choi J</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JK%22">Kim JK</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+I%22">Jung I</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+SW%22">Lim SW</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YR%22">Kim YR</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yang+AY%22">Yang AY</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+B%22">Lee B</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SE%22">Park SE</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+M%22">Shin M</searchLink>; College of Pharmacy, Korea University, Sejong, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+BB%22">Park BB</searchLink>; College of Pharmacy, Korea University, Sejong, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; College of Pharmacy, Korea University, Sejong, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+BC%22">Oh BC</searchLink>; Department of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Deredge+D%22">Deredge D</searchLink>; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wintrode+PL%22">Wintrode PL</searchLink>; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kim+MY%22">Kim MY</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Byun+Y%22">Byun Y</searchLink>; College of Pharmacy, Korea University, Sejong, Republic of Korea; Interdisciplinary Major Program in Innovative Pharmaceutical Sciences, Korea University, Sejong, Republic of Korea. Electronic address: yjbyun1@korea.ac.kr.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea; KAIST Institute for the BioCentury, KAIST, Daejeon, Republic of Korea; KAIST Stem Cell Center, KAIST, Daejeon, Republic of Korea. Electronic address: seyunkim@kaist.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2026 May 21; Vol. 33 (5), pp. 637-648.e10. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676030 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2451-9448 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224519448%22">24519448 </searchLink><i>NLM ISO Abbreviation: </i>Cell Chem Biol <i>Subsets: </i>MEDLINE
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