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Influenza vaccine responses differ between young children previously exposed to influenza antigens via infection versus vaccination.

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Title: Influenza vaccine responses differ between young children previously exposed to influenza antigens via infection versus vaccination.
Authors: Fox A; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. annette.fox@unimelb.edu.au.; Department of Infectious Diseases, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. annette.fox@unimelb.edu.au., Alafaci A; Royal Children's Hospital & Murdoch Children's Research Institute, Melbourne, Australia., Carolan L; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Burrell R; The Children's Hospital at Westmead, Sydney, Australia., Sánchez-Ovando S; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Infectious Diseases, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Hadiprodjo AJ; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Infectious Diseases, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., McMinn A; Royal Children's Hospital & Murdoch Children's Research Institute, Melbourne, Australia., Macartney K; The Children's Hospital at Westmead, Sydney, Australia.; Faculty of Medicine and Health, University of Sydney, Sydney, Australia.; The National Centre for Immunisation Research and Surveillance, Sydney, Australia., León AN; Department of Integrative Structural and Computational Biology (DISCoBio) at The Scripps Research Institute, La Jolla, CA, USA., Ward AB; Department of Integrative Structural and Computational Biology (DISCoBio) at The Scripps Research Institute, La Jolla, CA, USA., Wheatley A; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Sullivan SG; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; School of Clinical Sciences, Monash University, Melbourne, Australia., Crawford NW; Royal Children's Hospital & Murdoch Children's Research Institute, Melbourne, Australia., Britton PN; The Children's Hospital at Westmead, Sydney, Australia.; Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Subbarao K; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
Source: Communications medicine [Commun Med (Lond)] 2026 May 01. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond)
Database: MEDLINE Ultimate
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  Data: Influenza vaccine responses differ between young children previously exposed to influenza antigens via infection versus vaccination.
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  Data: <searchLink fieldCode="AU" term="%22Fox+A%22">Fox A</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. annette.fox@unimelb.edu.au.; Department of Infectious Diseases, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. annette.fox@unimelb.edu.au.<br /><searchLink fieldCode="AU" term="%22Alafaci+A%22">Alafaci A</searchLink>; Royal Children's Hospital & Murdoch Children's Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Carolan+L%22">Carolan L</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Burrell+R%22">Burrell R</searchLink>; The Children's Hospital at Westmead, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Sánchez-Ovando+S%22">Sánchez-Ovando S</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Infectious Diseases, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Hadiprodjo+AJ%22">Hadiprodjo AJ</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Infectious Diseases, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22McMinn+A%22">McMinn A</searchLink>; Royal Children's Hospital & Murdoch Children's Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Macartney+K%22">Macartney K</searchLink>; The Children's Hospital at Westmead, Sydney, Australia.; Faculty of Medicine and Health, University of Sydney, Sydney, Australia.; The National Centre for Immunisation Research and Surveillance, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22León+AN%22">León AN</searchLink>; Department of Integrative Structural and Computational Biology (DISCoBio) at The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology (DISCoBio) at The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wheatley+A%22">Wheatley A</searchLink>; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Sullivan+SG%22">Sullivan SG</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; School of Clinical Sciences, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Crawford+NW%22">Crawford NW</searchLink>; Royal Children's Hospital & Murdoch Children's Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Britton+PN%22">Britton PN</searchLink>; The Children's Hospital at Westmead, Sydney, Australia.; Faculty of Medicine and Health, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Subbarao+K%22">Subbarao K</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Portfolio%22">Nature Portfolio </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918250414506676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2730-664X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222730664X%22">2730664X </searchLink><i>NLM ISO Abbreviation: </i>Commun Med (Lond)
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        Value: 10.1038/s43856-026-01610-w
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              Text: 2026 May 01
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