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Pathogenic PF4/Polyanion ELISA-Negative Antibodies in HIT.

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Title: Pathogenic PF4/Polyanion ELISA-Negative Antibodies in HIT.
Authors: Kanack AJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Splinter NP; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Mauch EE; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Tefera L; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Gil MR; Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA., Jasra S; Department of Medicine, University of Vermont, Burlington, Vermont, USA., Goodwin A; Department of Pathology, University of Vermont, Burlington, Vermont, USA., Smock KJ; Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, Utah, USA.; ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA., Ahmad H; Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Ashrani A; Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Robinson NL; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA., Casanegra AI; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA., Jones CG; Retham Technologies, Wauwatosa, Wisconsin, USA., Pechauer SM; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA., Yttre E; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA., Aster RH; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA., Kohlhagen MC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Leger RR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Johns G; Department of Laboratory Medicine & Pathology, Mayo Clinic, Jacksonville, Florida, USA., Murray DL; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Zhou L; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA., Wang D; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA., Wen R; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA., Chen D; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Pruthi RK; Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Padmanabhan A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Source: American journal of hematology [Am J Hematol] 2026 Aug; Vol. 101 (8), pp. 1790-1798. Date of Electronic Publication: 2026 May 02.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pathogenic PF4/Polyanion ELISA-Negative Antibodies in HIT.
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  Data: <searchLink fieldCode="AU" term="%22Kanack+AJ%22">Kanack AJ</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Splinter+NP%22">Splinter NP</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Mauch+EE%22">Mauch EE</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Tefera+L%22">Tefera L</searchLink>; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Gil+MR%22">Gil MR</searchLink>; Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Jasra+S%22">Jasra S</searchLink>; Department of Medicine, University of Vermont, Burlington, Vermont, USA.<br /><searchLink fieldCode="AU" term="%22Goodwin+A%22">Goodwin A</searchLink>; Department of Pathology, University of Vermont, Burlington, Vermont, USA.<br /><searchLink fieldCode="AU" term="%22Smock+KJ%22">Smock KJ</searchLink>; Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, Utah, USA.; ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Ahmad+H%22">Ahmad H</searchLink>; Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Ashrani+A%22">Ashrani A</searchLink>; Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+NL%22">Robinson NL</searchLink>; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Casanegra+AI%22">Casanegra AI</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Jones+CG%22">Jones CG</searchLink>; Retham Technologies, Wauwatosa, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Pechauer+SM%22">Pechauer SM</searchLink>; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Yttre+E%22">Yttre E</searchLink>; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Aster+RH%22">Aster RH</searchLink>; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Kohlhagen+MC%22">Kohlhagen MC</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Leger+RR%22">Leger RR</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Johns+G%22">Johns G</searchLink>; Department of Laboratory Medicine & Pathology, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Murray+DL%22">Murray DL</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Wen+R%22">Wen R</searchLink>; Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Pruthi+RK%22">Pruthi RK</searchLink>; Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Padmanabhan+A%22">Padmanabhan A</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%227610369%22">American journal of hematology</searchLink> [Am J Hematol] 2026 Aug; Vol. 101 (8), pp. 1790-1798. <i>Date of Electronic Publication: </i>2026 May 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7610369 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-8652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203618609%22">03618609 </searchLink><i>NLM ISO Abbreviation: </i>Am J Hematol <i>Subsets: </i>MEDLINE
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              Text: 2026 Aug
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