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High-throughput human microfluidic organoid-on-a-chip platform for modeling liver diseases and screening nanotherapeutics.

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Title: High-throughput human microfluidic organoid-on-a-chip platform for modeling liver diseases and screening nanotherapeutics.
Authors: Kong D; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. kongdefu@sjtu.edu.cn.; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. kongdefu@sjtu.edu.cn., Yu S; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Heegsma J; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Blokzijl T; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Qin T; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Pan Y; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Blokzijl H; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Meijer VE; Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Duan Y; State Key Laboratory of Systems Medicine for Cancer, Renji Hospital, School of Medicine, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, 200032, China., Faber KN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. k.n.faber@umcg.nl., Xia Q; Department of Liver Surgery and Liver Transplantation, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. xiaqiang@shsmu.edu.cn., He K; Department of Liver Surgery and Liver Transplantation, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. hekang@renji.com.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 May 02; Vol. 24 (1). Date of Electronic Publication: 2026 May 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-throughput human microfluidic organoid-on-a-chip platform for modeling liver diseases and screening nanotherapeutics.
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  Data: <searchLink fieldCode="AU" term="%22Kong+D%22">Kong D</searchLink>; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. kongdefu@sjtu.edu.cn.; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. kongdefu@sjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+S%22">Yu S</searchLink>; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Heegsma+J%22">Heegsma J</searchLink>; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Blokzijl+T%22">Blokzijl T</searchLink>; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Qin+T%22">Qin T</searchLink>; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pan+Y%22">Pan Y</searchLink>; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Blokzijl+H%22">Blokzijl H</searchLink>; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Meijer+VE%22">de Meijer VE</searchLink>; Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Duan+Y%22">Duan Y</searchLink>; State Key Laboratory of Systems Medicine for Cancer, Renji Hospital, School of Medicine, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Faber+KN%22">Faber KN</searchLink>; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. k.n.faber@umcg.nl.<br /><searchLink fieldCode="AU" term="%22Xia+Q%22">Xia Q</searchLink>; Department of Liver Surgery and Liver Transplantation, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. xiaqiang@shsmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22He+K%22">He K</searchLink>; Department of Liver Surgery and Liver Transplantation, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. hekang@renji.com.
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  Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2026 May 02; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 May 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12951-026-04477-0
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      – TitleFull: High-throughput human microfluidic organoid-on-a-chip platform for modeling liver diseases and screening nanotherapeutics.
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            – D: 02
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              Text: 2026 May 02
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              Y: 2026
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