Evidence for frequency-dependent neuronal "wind-up" origin of temporal summation of pain - an experimental crossover investigation.

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Title: Evidence for frequency-dependent neuronal "wind-up" origin of temporal summation of pain - an experimental crossover investigation.
Authors: Bremer M; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany., Janner H; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany., Hizhko V; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany., Nowak A; Department of Anesthesiology, Intensive Medicine, Emergency Medicine and Pain Therapy, Hospital Dresden-Friedrichstadt, Dresden, Germany., Busemann A; Department of Surgery, University Medicine of Greifswald, Greifswald, Germany., Hahnenkamp K; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany., Usichenko TI; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany.; Department of Anesthesia, McMaster University, Hamilton, Canada.
Source: Scandinavian journal of pain [Scand J Pain] 2026 May 04; Vol. 26 (1). Date of Electronic Publication: 2026 May 04 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: De Gruyter Country of Publication: Germany NLM ID: 101520867 Publication Model: eCollection Cited Medium: Internet ISSN: 1877-8879 (Electronic) Linking ISSN: 18778860 NLM ISO Abbreviation: Scand J Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Evidence for frequency-dependent neuronal "wind-up" origin of temporal summation of pain - an experimental crossover investigation.
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  Data: <searchLink fieldCode="AU" term="%22Bremer+M%22">Bremer M</searchLink>; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Janner+H%22">Janner H</searchLink>; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Hizhko+V%22">Hizhko V</searchLink>; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Nowak+A%22">Nowak A</searchLink>; Department of Anesthesiology, Intensive Medicine, Emergency Medicine and Pain Therapy, Hospital Dresden-Friedrichstadt, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Busemann+A%22">Busemann A</searchLink>; Department of Surgery, University Medicine of Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Hahnenkamp+K%22">Hahnenkamp K</searchLink>; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Usichenko+TI%22">Usichenko TI</searchLink>; Department of Anesthesiology, University Medicine of Greifswald, Greifswald, Germany.; Department of Anesthesia, McMaster University, Hamilton, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101520867%22">Scandinavian journal of pain</searchLink> [Scand J Pain] 2026 May 04; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 May 04 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22De+Gruyter%22">De Gruyter </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101520867 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1877-8879 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218778860%22">18778860 </searchLink><i>NLM ISO Abbreviation: </i>Scand J Pain <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1515/sjpain-2026-0009
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      – Code: eng
        Text: English
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              Text: 2026 May 04
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              Value: 26
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