Rapid Quantification of Ceftobiprole in Human Plasma and Cerebrospinal Fluid by LC-MS/MS and Its Application in Patients with Central Nervous System Infections.
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| Title: | Rapid Quantification of Ceftobiprole in Human Plasma and Cerebrospinal Fluid by LC-MS/MS and Its Application in Patients with Central Nervous System Infections. |
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| Authors: | Ablimit S; College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China., Li W; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China., Chen M; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China., Zhang J; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China.; Clinical Pharmacology Research Center, Huashan Hospital, Fudan University, Shanghai 200040, China., Li N; Clinical Pharmacology Research Center, Huashan Hospital, Fudan University, Shanghai 200040, China., Fan Y; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China., Yasen M; College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China., Iminjan M; College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China., Guo B; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China. |
| Source: | Molecules (Basel, Switzerland) [Molecules] 2026 Apr 10; Vol. 31 (8). Date of Electronic Publication: 2026 Apr 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42075931 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Rapid Quantification of Ceftobiprole in Human Plasma and Cerebrospinal Fluid by LC-MS/MS and Its Application in Patients with Central Nervous System Infections. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ablimit+S%22">Ablimit S</searchLink>; College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China.; Clinical Pharmacology Research Center, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Clinical Pharmacology Research Center, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Yasen+M%22">Yasen M</searchLink>; College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China.<br /><searchLink fieldCode="AU" term="%22Iminjan+M%22">Iminjan M</searchLink>; College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China.<br /><searchLink fieldCode="AU" term="%22Guo+B%22">Guo B</searchLink>; Institute of Antibiotics, Key Laboratory of Clinical Pharmacology of Antibiotics, National Clinical Research Center for Aging and Medicine, Professional Technical Service Platform for Comprehensive Preclinical Pharmacodynamic Evaluation and Clinical Translation of Antibacterial Agents, Joint Laboratory of Hospital & Enterprise for Pathogen Diagnosis of Drug-Resistant Bacterial lnfections and lnnovative Drug R&D, Huashan Hospital, Fudan University, Shanghai 200040, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100964009%22">Molecules (Basel, Switzerland)</searchLink> [Molecules] 2026 Apr 10; Vol. 31 (8). <i>Date of Electronic Publication: </i>2026 Apr 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>100964009 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-3049 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214203049%22">14203049 </searchLink><i>NLM ISO Abbreviation: </i>Molecules <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42075931 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/molecules31081252 Languages: – Code: eng Text: English Titles: – TitleFull: Rapid Quantification of Ceftobiprole in Human Plasma and Cerebrospinal Fluid by LC-MS/MS and Its Application in Patients with Central Nervous System Infections. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ablimit S – PersonEntity: Name: NameFull: Li W – PersonEntity: Name: NameFull: Chen M – PersonEntity: Name: NameFull: Zhang J – PersonEntity: Name: NameFull: Li N – PersonEntity: Name: NameFull: Fan Y – PersonEntity: Name: NameFull: Yasen M – PersonEntity: Name: NameFull: Iminjan M – PersonEntity: Name: NameFull: Guo B IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 04 Text: 2026 Apr 10 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1420-3049 Numbering: – Type: volume Value: 31 – Type: issue Value: 8 Titles: – TitleFull: Molecules (Basel, Switzerland) Type: main |
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