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Hypoxemia and hypercapnia synergistically mediate peripheral vasoconstriction, whereas hypercapnia mediates cerebral vasodilation in resting humans.

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Title: Hypoxemia and hypercapnia synergistically mediate peripheral vasoconstriction, whereas hypercapnia mediates cerebral vasodilation in resting humans.
Authors: Horiuchi M; Faculty of Sports and Life Science, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan., Moriyama S; Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan., Nishiyasu T; Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.; Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, Tsukuba, Japan., Fujii N; Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.; Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, Tsukuba, Japan.
Source: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2026 Jun 01; Vol. 330 (6), pp. R631-R638. Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1490 (Electronic) Linking ISSN: 03636119 NLM ISO Abbreviation: Am J Physiol Regul Integr Comp Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hypoxemia and hypercapnia synergistically mediate peripheral vasoconstriction, whereas hypercapnia mediates cerebral vasodilation in resting humans.
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  Data: <searchLink fieldCode="AU" term="%22Horiuchi+M%22">Horiuchi M</searchLink>; Faculty of Sports and Life Science, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Moriyama+S%22">Moriyama S</searchLink>; Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Nishiyasu+T%22">Nishiyasu T</searchLink>; Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.; Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Fujii+N%22">Fujii N</searchLink>; Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.; Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, Tsukuba, Japan.
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  Data: <searchLink fieldCode="JN" term="%22100901230%22">American journal of physiology. Regulatory, integrative and comparative physiology</searchLink> [Am J Physiol Regul Integr Comp Physiol] 2026 Jun 01; Vol. 330 (6), pp. R631-R638. <i>Date of Electronic Publication: </i>2026 May 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Physiological+Society%22">American Physiological Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100901230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-1490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203636119%22">03636119 </searchLink><i>NLM ISO Abbreviation: </i>Am J Physiol Regul Integr Comp Physiol <i>Subsets: </i>MEDLINE
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        Value: 10.1152/ajpregu.00085.2026
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      – Code: eng
        Text: English
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      – TitleFull: Hypoxemia and hypercapnia synergistically mediate peripheral vasoconstriction, whereas hypercapnia mediates cerebral vasodilation in resting humans.
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            NameFull: Moriyama S
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              Text: 2026 Jun 01
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