A loss of function variant in SLC30A8/ZnT8 drives proteomic changes associated with lowered apoptosis in human stem cell-derived islets.
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| Title: | A loss of function variant in SLC30A8/ZnT8 drives proteomic changes associated with lowered apoptosis in human stem cell-derived islets. |
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| Authors: | Gasser M; Centre Hospitalier de l'Université de Montréal (CHUM) Research Center and Department of Medicine, University of Montreal, Montreal, QC, Canada., Cherkaoui I; Centre Hospitalier de l'Université de Montréal (CHUM) Research Center and Department of Medicine, University of Montreal, Montreal, QC, Canada., Ostinelli G; Centre Hospitalier de l'Université de Montréal (CHUM) Research Center and Department of Medicine, University of Montreal, Montreal, QC, Canada., Ferron M; Institut de Recherche Clinique de Montréal and Department of Medicine, University of Montreal, Montreal, QC, Canada., Du Q; Columbia University, New York, NY, USA., Egli D; Columbia University, New York, NY, USA., Rutter GA; Centre Hospitalier de l'Université de Montréal (CHUM) Research Center and Department of Medicine, University of Montreal, Montreal, QC, Canada.; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, United Kingdom.; Lee Kong Chian School of Medicine, Nanyang Technological, University, Singapore, Singapore.; Research institute of the McGill University Health Sciences Centre, Montreal, QC, Canada. |
| Source: | MedRxiv : the preprint server for health sciences [medRxiv] 2026 Apr 20. Date of Electronic Publication: 2026 Apr 20. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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