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Multiplexed CRISPR base editing enables pulse-activated irreversible biocontainment of engineered bacteria.

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Title: Multiplexed CRISPR base editing enables pulse-activated irreversible biocontainment of engineered bacteria.
Authors: Cho SW; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea., Kim T; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea., Yang J; Department of Chemical Engineering, Jeju National University, 102 Jejudaehak-ro, Jeju-si, Jeju-do 63243, South Korea., Byun G; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea., Seo SW; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea.; Institute of Chemical Processes, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.; Bio-MAX Institute, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.; Institute of Bio Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.; Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Apr 23; Vol. 54 (8).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multiplexed CRISPR base editing enables pulse-activated irreversible biocontainment of engineered bacteria.
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  Data: <searchLink fieldCode="AU" term="%22Cho+SW%22">Cho SW</searchLink>; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+T%22">Kim T</searchLink>; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Department of Chemical Engineering, Jeju National University, 102 Jejudaehak-ro, Jeju-si, Jeju-do 63243, South Korea.<br /><searchLink fieldCode="AU" term="%22Byun+G%22">Byun G</searchLink>; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Seo+SW%22">Seo SW</searchLink>; Department of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-Gu, Seoul 08826, Republic of Korea.; Institute of Chemical Processes, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.; Bio-MAX Institute, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.; Institute of Bio Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.; Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.
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  Data: <searchLink fieldCode="JN" term="%220411011%22">Nucleic acids research</searchLink> [Nucleic Acids Res] 2026 Apr 23; Vol. 54 (8).
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        Value: 10.1093/nar/gkag422
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              Text: 2026 Apr 23
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