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Temporal trends and prognostic factors in critically ill adult patients with acute leukemia: an individual participant data meta-analysis.

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Title: Temporal trends and prognostic factors in critically ill adult patients with acute leukemia: an individual participant data meta-analysis.
Authors: Chean D; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France.; European Society of Intensive Care Medicine (ESICM) Methodology Group, Brussels, Belgium., Dupont T; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France., Nates JL; Division of Anesthesiology, Critical Care, and Pain Medicine, Department of Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Manjappachar NK; Division of Anesthesiology, Critical Care, and Pain Medicine, Department of Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Medic M; Intensive Care Unit, Department of Internal Medicine, University Hospital Centre Zagreb, Zagreb, Croatia., Aygencel G; Division of Intensive Care Medicine, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey., Orvain C; Maladies du Sang, CHU d'Angers, Angers, France., Kouatchet A; Medical Intensive Care Unit, CHU d'Angers, Angers, France., Sheshadri A; Division of Internal Medicine, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA., Haque TK; Division of Internal Medicine, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA., Russell L; Copenhagen University Hospital Gentofte, Hellerup, Denmark., Pabst T; Department of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland., Turkoglu M; Division of Intensive Care Medicine, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey., Ostermann M; Guy's and St Thomas' NHS Foundation Trust, Department of Critical Care, King's College London, Westminster Bridge Road, London, UK., Soares M; Department of Critical Care and Postgraduate Program, D'Or Institute for Research and Education, Rio de Janeiro, Brazil., Cetintepe T; Department of Hematology, Ataturk Training and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey., Buckstein R; Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada., Issa N; Internal Medicine and Infectious Disease Unit, Groupe Saint-André, University Hospital, Bordeaux, France., Mokart D; Department of Anesthesiology and Critical Care, Paoli-Calmettes Institute, Marseille, France., Caruso P; Intensive Care Unit, AC Camargo Cancer Center, São Paulo, Brazil., Cornejo-Juarez P; Department of Infectious Diseases, Instituto Nacional de Cancerología, Mexico City, Mexico., Schnell D; Medical-Surgical Intensive Care Unit, Angoulême Hospital, Angoulême, France., Lahmer T; Technical University Munich (TUM) School of Medicine and Health, Department of Clinical Medicine-Clinical Department for Internal Medicine II, University Medical Center, TUM, Munich, Germany., Fodil S; Hematology Department, Saint-Louis Teaching Hospital, Paris, France., Lengliné E; Hematology Department, Saint-Louis Teaching Hospital, Paris, France., Luque-Paz D; Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France., Lemiale V; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France., Poole D; European Society of Intensive Care Medicine (ESICM) Methodology Group, Brussels, Belgium.; Operative Unit of Anesthesia and Intensive Care, S. Martino Hospital, Belluno, Italy., Darmon M; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France.; European Society of Intensive Care Medicine (ESICM) Methodology Group, Brussels, Belgium., Azoulay E; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France. elie.azoulay@aphp.fr.
Source: Intensive care medicine [Intensive Care Med] 2026 Jun; Vol. 52 (6), pp. 1210-1221. Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Chean+D%22">Chean D</searchLink>; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France.; European Society of Intensive Care Medicine (ESICM) Methodology Group, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Dupont+T%22">Dupont T</searchLink>; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France.<br /><searchLink fieldCode="AU" term="%22Nates+JL%22">Nates JL</searchLink>; Division of Anesthesiology, Critical Care, and Pain Medicine, Department of Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Manjappachar+NK%22">Manjappachar NK</searchLink>; Division of Anesthesiology, Critical Care, and Pain Medicine, Department of Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Medic+M%22">Medic M</searchLink>; Intensive Care Unit, Department of Internal Medicine, University Hospital Centre Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Aygencel+G%22">Aygencel G</searchLink>; Division of Intensive Care Medicine, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Orvain+C%22">Orvain C</searchLink>; Maladies du Sang, CHU d'Angers, Angers, France.<br /><searchLink fieldCode="AU" term="%22Kouatchet+A%22">Kouatchet A</searchLink>; Medical Intensive Care Unit, CHU d'Angers, Angers, France.<br /><searchLink fieldCode="AU" term="%22Sheshadri+A%22">Sheshadri A</searchLink>; Division of Internal Medicine, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Haque+TK%22">Haque TK</searchLink>; Division of Internal Medicine, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Russell+L%22">Russell L</searchLink>; Copenhagen University Hospital Gentofte, Hellerup, Denmark.<br /><searchLink fieldCode="AU" term="%22Pabst+T%22">Pabst T</searchLink>; Department of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Turkoglu+M%22">Turkoglu M</searchLink>; Division of Intensive Care Medicine, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Ostermann+M%22">Ostermann M</searchLink>; Guy's and St Thomas' NHS Foundation Trust, Department of Critical Care, King's College London, Westminster Bridge Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Soares+M%22">Soares M</searchLink>; Department of Critical Care and Postgraduate Program, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Cetintepe+T%22">Cetintepe T</searchLink>; Department of Hematology, Ataturk Training and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey.<br /><searchLink fieldCode="AU" term="%22Buckstein+R%22">Buckstein R</searchLink>; Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Issa+N%22">Issa N</searchLink>; Internal Medicine and Infectious Disease Unit, Groupe Saint-André, University Hospital, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Mokart+D%22">Mokart D</searchLink>; Department of Anesthesiology and Critical Care, Paoli-Calmettes Institute, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Caruso+P%22">Caruso P</searchLink>; Intensive Care Unit, AC Camargo Cancer Center, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Cornejo-Juarez+P%22">Cornejo-Juarez P</searchLink>; Department of Infectious Diseases, Instituto Nacional de Cancerología, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Schnell+D%22">Schnell D</searchLink>; Medical-Surgical Intensive Care Unit, Angoulême Hospital, Angoulême, France.<br /><searchLink fieldCode="AU" term="%22Lahmer+T%22">Lahmer T</searchLink>; Technical University Munich (TUM) School of Medicine and Health, Department of Clinical Medicine-Clinical Department for Internal Medicine II, University Medical Center, TUM, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fodil+S%22">Fodil S</searchLink>; Hematology Department, Saint-Louis Teaching Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lengliné+E%22">Lengliné E</searchLink>; Hematology Department, Saint-Louis Teaching Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Luque-Paz+D%22">Luque-Paz D</searchLink>; Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Lemiale+V%22">Lemiale V</searchLink>; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France.<br /><searchLink fieldCode="AU" term="%22Poole+D%22">Poole D</searchLink>; European Society of Intensive Care Medicine (ESICM) Methodology Group, Brussels, Belgium.; Operative Unit of Anesthesia and Intensive Care, S. Martino Hospital, Belluno, Italy.<br /><searchLink fieldCode="AU" term="%22Darmon+M%22">Darmon M</searchLink>; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France.; European Society of Intensive Care Medicine (ESICM) Methodology Group, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Azoulay+E%22">Azoulay E</searchLink>; Medical Intensive Care Unit, AP-HP, Saint-Louis Teaching Hospital, Paris-Cité University, INSERM UMR1342 Institut de Recherche Saint-Louis, Paris, France. elie.azoulay@aphp.fr.
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