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Identification of a Potential Direct-Acting DNA Ethylating Agent Originating from the Synthetic Cooling Agent N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide (WS-3).

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Title: Identification of a Potential Direct-Acting DNA Ethylating Agent Originating from the Synthetic Cooling Agent N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide (WS-3).
Authors: Ostlund T; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States., Dameh NF; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States., Luedtke MW; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States., Carmella SG; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States., Hecht SS; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Source: Chemical research in toxicology [Chem Res Toxicol] 2026 May 18; Vol. 39 (5), pp. 948-956. Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5010 (Electronic) Linking ISSN: 0893228X NLM ISO Abbreviation: Chem Res Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ostlund+T%22">Ostlund T</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Dameh+NF%22">Dameh NF</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Luedtke+MW%22">Luedtke MW</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Carmella+SG%22">Carmella SG</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Hecht+SS%22">Hecht SS</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8807448 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5010 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220893228X%22">0893228X </searchLink><i>NLM ISO Abbreviation: </i>Chem Res Toxicol <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.chemrestox.6c00069
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        Text: English
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      – TitleFull: Identification of a Potential Direct-Acting DNA Ethylating Agent Originating from the Synthetic Cooling Agent N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide (WS-3).
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              Text: 2026 May 18
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