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Succinate calls a time-out on pyrimidine biosynthesis.

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Title: Succinate calls a time-out on pyrimidine biosynthesis.
Authors: Schatton D; Faculty of Medicine, University of Cologne, and University Hospital Cologne, Institute for Metabolomics in Ageing, Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), Cologne, Germany.; Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany., Frezza C; Faculty of Medicine, University of Cologne, and University Hospital Cologne, Institute for Metabolomics in Ageing, Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), Cologne, Germany. christian.frezza@uni-koeln.de.; Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany. christian.frezza@uni-koeln.de.; Faculty of Mathematics and Natural Sciences, University of Cologne, Institute of Genetics, Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany. christian.frezza@uni-koeln.de.
Source: Nature metabolism [Nat Metab] 2026 Jun; Vol. 8 (6), pp. 1253-1255.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:2522-5812
DOI:10.1038/s42255-026-01523-x