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Exogenous 8-hydroxydeoxyguanosine prevents liver fibrosis through the regulation of Rac1-NADPH oxidase signaling in a metabolic dysfunction-associated steatohepatitis model.

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Title: Exogenous 8-hydroxydeoxyguanosine prevents liver fibrosis through the regulation of Rac1-NADPH oxidase signaling in a metabolic dysfunction-associated steatohepatitis model.
Authors: Lee Y; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Kim IS; Department of Microbiology, Gachon University College of Medicine, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea., Kim JW; College of Medicine, Gachon University, Incheon, Republic of Korea., Kim MK; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Chae YG; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Choi CS; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea., Kwon OS; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Kim YS; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Kim JH; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Chung DH; Department of Pathology, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Shin SK; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.
Source: Free radical research [Free Radic Res] 2026 May 11, pp. 1-12. Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9423872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2470 (Electronic) Linking ISSN: 10292470 NLM ISO Abbreviation: Free Radic Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1029-2470
DOI:10.1080/10715762.2026.2668102