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Deupirfenidone Compared with Pirfenidone and Placebo in Idiopathic Pulmonary Fibrosis (ELEVATE-IPF): a Phase 2b Randomized Placebo-Controlled Trial.

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Title: Deupirfenidone Compared with Pirfenidone and Placebo in Idiopathic Pulmonary Fibrosis (ELEVATE-IPF): a Phase 2b Randomized Placebo-Controlled Trial.
Authors: Maher TM; National Heart and Lung Institute, Imperial College, London, United Kingdom and Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Hamblin MJ; Internal Medicine, University of Kansas Medical Center, Kansas City, KS, United States., Choi WI; Dept. of Internal Medicine, Hanyang University, Myongji Hospital, Goyang-si, Republic of Korea., Case AH; Pulmonary, Critical Care, and Sleep, Piedmont Healthcare, Atlanta, GA, United States., Tomos IP; 5th Pulmonary Medicine Department, SOTIRIA Chest Diseases Hospital of Athens, Athens, Greece., Tzouvelekis AE; Department of Respiratory Medicine, University of Patras, PATRAS, Greece., Shore JE; Pulmonary Fibrosis Foundation, Chicago, IL, United States., Bergna MA; Research, CEMER, FL, Vicente López, Argentina., Golod D; PureTech Health, Boston, MA, United States., Elenko E; PureTech Health, Boston, MA, United States., Zhang Y; PureTech Health, Boston, MA, United States., Graham CS; PureTech Health, Boston, MA, United States., Song JW; Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kulkarni T; Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Corporate Authors: ELEVATE IPF Investigators (listed in Supplementary Appendix)
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2026 Apr 02. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 9421642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Maher+TM%22">Maher TM</searchLink>; National Heart and Lung Institute, Imperial College, London, United Kingdom and Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Hamblin+MJ%22">Hamblin MJ</searchLink>; Internal Medicine, University of Kansas Medical Center, Kansas City, KS, United States.<br /><searchLink fieldCode="AU" term="%22Choi+WI%22">Choi WI</searchLink>; Dept. of Internal Medicine, Hanyang University, Myongji Hospital, Goyang-si, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Case+AH%22">Case AH</searchLink>; Pulmonary, Critical Care, and Sleep, Piedmont Healthcare, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Tomos+IP%22">Tomos IP</searchLink>; 5th Pulmonary Medicine Department, SOTIRIA Chest Diseases Hospital of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tzouvelekis+AE%22">Tzouvelekis AE</searchLink>; Department of Respiratory Medicine, University of Patras, PATRAS, Greece.<br /><searchLink fieldCode="AU" term="%22Shore+JE%22">Shore JE</searchLink>; Pulmonary Fibrosis Foundation, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Bergna+MA%22">Bergna MA</searchLink>; Research, CEMER, FL, Vicente López, Argentina.<br /><searchLink fieldCode="AU" term="%22Golod+D%22">Golod D</searchLink>; PureTech Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Elenko+E%22">Elenko E</searchLink>; PureTech Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; PureTech Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Graham+CS%22">Graham CS</searchLink>; PureTech Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Song+JW%22">Song JW</searchLink>; Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kulkarni+T%22">Kulkarni T</searchLink>; Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
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  Data: <searchLink fieldCode="CA" term="%22ELEVATE+IPF+Investigators+%28listed+in+Supplementary+Appendix%29%22">ELEVATE IPF Investigators (listed in Supplementary Appendix)</searchLink>
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