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Triple-Mutated HSV-1 Expressing Soluble B7-1 Plus CTLA-4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer.

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Title: Triple-Mutated HSV-1 Expressing Soluble B7-1 Plus CTLA-4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer.
Authors: Sugauchi A; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan., Uchihashi T; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan., Ito H; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Iwai M; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Tsurumaki Sato Y; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Kurioka K; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan., Usta SZ; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan., Tanaka M; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Kogo M; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan., Tanaka S; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan., Fukuhara H; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.; Department of Urology, Kyorin University School of Medicine, Tokyo, Japan., Todo T; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Source: Cancer science [Cancer Sci] 2026 Jul; Vol. 117 (7), pp. 1961-1974. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Triple-Mutated HSV-1 Expressing Soluble B7-1 Plus CTLA-4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Sugauchi+A%22">Sugauchi A</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Uchihashi+T%22">Uchihashi T</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+H%22">Ito H</searchLink>; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Iwai+M%22">Iwai M</searchLink>; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tsurumaki+Sato+Y%22">Tsurumaki Sato Y</searchLink>; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kurioka+K%22">Kurioka K</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Usta+SZ%22">Usta SZ</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+M%22">Tanaka M</searchLink>; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kogo+M%22">Kogo M</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+S%22">Tanaka S</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fukuhara+H%22">Fukuhara H</searchLink>; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.; Department of Urology, Kyorin University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Todo+T%22">Todo T</searchLink>; Division of Innovative Cancer Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101168776%22">Cancer science</searchLink> [Cancer Sci] 2026 Jul; Vol. 117 (7), pp. 1961-1974. <i>Date of Electronic Publication: </i>2026 May 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+Publishing+on+behalf+of+the+Japanese+Cancer+Association%22">Wiley Publishing on behalf of the Japanese Cancer Association </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101168776 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1349-7006 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213479032%22">13479032 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1111/cas.70410
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        Text: English
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      – TitleFull: Triple-Mutated HSV-1 Expressing Soluble B7-1 Plus CTLA-4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer.
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              Text: 2026 Jul
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