Monovalent and multivalent OspA mRNA-LNP vaccines elicit functional antibodies and protect against Borrelia burgdorferi in mice.
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| Title: | Monovalent and multivalent OspA mRNA-LNP vaccines elicit functional antibodies and protect against Borrelia burgdorferi in mice. |
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| Authors: | Finn MB; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Willsey G; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Piazza CL; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Clendenen L; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA., Shrestha M; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA., You SS; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA., Ma L; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Dhingra Y; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Laciak AR; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Uggowitzer KA; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Obiero JM; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Freeman-Gallant G; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Natarajan H; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Green S; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Pirayesh E; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Lai YT; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Himansu S; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Carfi A; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Hu LT; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA., Mantis N; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Plante O; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA., Dold C; Infectious Disease Research, Moderna, Inc., Cambridge, MA, USA. Christina.Dold@modernatx.com. |
| Source: | NPJ vaccines [NPJ Vaccines] 2026 May 05. Date of Electronic Publication: 2026 May 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines |
| Database: | MEDLINE Ultimate |
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