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Targeting NUDT21-mediated alternative polyadenylation of oncogenes ameliorates colorectal cancer malignancy and metastasis.

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Title: Targeting NUDT21-mediated alternative polyadenylation of oncogenes ameliorates colorectal cancer malignancy and metastasis.
Authors: Lin SC; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Jaylin@mail.ncku.edu.tw.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Jaylin@mail.ncku.edu.tw.; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Jaylin@mail.ncku.edu.tw., Tsai YC; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC., Wang JL; National Laboratory Animal Center, National Applied Research Laboratories, Tainan, Taiwan, ROC., Chin HJ; National Laboratory Animal Center, National Applied Research Laboratories, Tainan, Taiwan, ROC., Tsai CC; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC., Lin SC; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC., Lin YS; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC., Lin BW; Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC., Tsai SJ; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. seantsai@ccu.edu.tw.; Department of Biomedical Sciences, College of Science, National Chung Cheng University, Chiayi, Taiwan, ROC. seantsai@ccu.edu.tw.
Source: British journal of cancer [Br J Cancer] 2026 May 06. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting NUDT21-mediated alternative polyadenylation of oncogenes ameliorates colorectal cancer malignancy and metastasis.
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  Data: <searchLink fieldCode="AU" term="%22Lin+SC%22">Lin SC</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Jaylin@mail.ncku.edu.tw.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Jaylin@mail.ncku.edu.tw.; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Jaylin@mail.ncku.edu.tw.<br /><searchLink fieldCode="AU" term="%22Tsai+YC%22">Tsai YC</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+JL%22">Wang JL</searchLink>; National Laboratory Animal Center, National Applied Research Laboratories, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chin+HJ%22">Chin HJ</searchLink>; National Laboratory Animal Center, National Applied Research Laboratories, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Tsai+CC%22">Tsai CC</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+SC%22">Lin SC</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+YS%22">Lin YS</searchLink>; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+BW%22">Lin BW</searchLink>; Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Tsai+SJ%22">Tsai SJ</searchLink>; Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. seantsai@ccu.edu.tw.; Department of Biomedical Sciences, College of Science, National Chung Cheng University, Chiayi, Taiwan, ROC. seantsai@ccu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2026 May 06. <i>Date of Electronic Publication: </i>2026 May 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41416-026-03451-9
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        Text: English
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              Text: 2026 May 06
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