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Cytosolic DNA inhibits rDNA transcription by retaining the RNA polymerase I transcription machinery.

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Title: Cytosolic DNA inhibits rDNA transcription by retaining the RNA polymerase I transcription machinery.
Authors: Xu Y; Laboratory of Basic Biology, Hunan First Normal University, Changsha, China. yinfengxu@hnfnu.edu.cn., Wang Q; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China., Qian C; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China., Lu S; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China., He Z; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China., Liu W; Department of Metabolic Medicine, International Institutes of Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China. liuwei666@zju.edu.cn., Wan W; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China. wanwei@zju.edu.cn.
Source: The EMBO journal [EMBO J] 2026 Jun; Vol. 45 (12), pp. 4153-4175. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cytosolic DNA inhibits rDNA transcription by retaining the RNA polymerase I transcription machinery.
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  Data: <searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Laboratory of Basic Biology, Hunan First Normal University, Changsha, China. yinfengxu@hnfnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Qian+C%22">Qian C</searchLink>; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lu+S%22">Lu S</searchLink>; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22He+Z%22">He Z</searchLink>; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Metabolic Medicine, International Institutes of Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China. liuwei666@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wan+W%22">Wan W</searchLink>; Department of Thoracic Surgery of Sir Run Run Shaw Hospital, and Department of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China. wanwei@zju.edu.cn.
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        Value: 10.1038/s44318-026-00792-2
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      – TitleFull: Cytosolic DNA inhibits rDNA transcription by retaining the RNA polymerase I transcription machinery.
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              Text: 2026 Jun
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