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Early-Life DNA methylation at TRIM6 and TTC23 promoters associates with respiratory infections at one year.

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Title: Early-Life DNA methylation at TRIM6 and TTC23 promoters associates with respiratory infections at one year.
Authors: Edwards K; Edwin S.H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Merrill SM; Edwin S.H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Psychology, University of Massachusetts Lowell, Lowell, MA, USA., Letourneau NL; Department of Kinesiology, University of Calgary, Calgary, AB, Canada.; Department of Pediatrics, University of Calgary, Calgary, AB, Canada.; Owerko Centre at the Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.; Department of Psychiatry, University of Calgary, Calgary, AB, Canada.; Faculty of Nursing and Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada., Konwar C; Edwin S.H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Gladish N; Edwin S.H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Epidemiology and Population Health, Stanford University, Palo Alto, CA, USA., MacIsaac JL; Edwin S.H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Giesbrecht GF; Department of Pediatrics, University of Calgary, Calgary, AB, Canada.; Owerko Centre at the Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada., Mandhane P; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada., Simons E; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.; Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada., Moraes TJ; Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Canada., Azad MB; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.; Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada., Subbarao P; Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Canada.; Department of Physiology & Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Turvey SE; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada., Ross KM; Department of Kinesiology, University of Calgary, Calgary, AB, Canada.; Department of Pediatrics, University of Calgary, Calgary, AB, Canada.; Owerko Centre at the Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.; Department of Psychiatry, University of Calgary, Calgary, AB, Canada.; Faculty of Humanities and Social Sciences, Athabasca University, Athabasca, AB, Canada., Kobor MS; Edwin S.H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada. michael.kobor@ubc.ca.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.
Source: Pediatric research [Pediatr Res] 2026 May 06. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 0100714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0447 (Electronic) Linking ISSN: 00313998 NLM ISO Abbreviation: Pediatr Res Subsets: MEDLINE
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