View in EDS

Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2.

Saved in:
Bibliographic Details
Title: Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2.
Authors: Anderson-Daniels J; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Diefenbacher MV; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Yount BL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Meganck RM; Department of Molecular Microbiology, Washington University in St Louis, St. Louis, Missouri, USA., Tse LV; Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, Missouri, USA., Burke KN; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Miranda HA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Scobey DT; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lu X; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Stevens L; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Dinnon KH 3rd; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Chapman NS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Pajon C; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Powers JM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Nguyen C; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Graham RL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Heaton NS; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Denison MR; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Source: MBio [mBio] 2026 Jun 10; Vol. 17 (6), pp. e0007326. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42089609
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Anderson-Daniels+J%22">Anderson-Daniels J</searchLink>; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Diefenbacher+MV%22">Diefenbacher MV</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Yount+BL%22">Yount BL</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Meganck+RM%22">Meganck RM</searchLink>; Department of Molecular Microbiology, Washington University in St Louis, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Tse+LV%22">Tse LV</searchLink>; Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Burke+KN%22">Burke KN</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Miranda+HA%22">Miranda HA</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Scobey+DT%22">Scobey DT</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Stevens+L%22">Stevens L</searchLink>; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Dinnon+KH+3rd%22">Dinnon KH 3rd</searchLink>; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+NS%22">Chapman NS</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Pajon+C%22">Pajon C</searchLink>; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Powers+JM%22">Powers JM</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+C%22">Nguyen C</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Graham+RL%22">Graham RL</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Heaton+NS%22">Heaton NS</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Baric+RS%22">Baric RS</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Denison+MR%22">Denison MR</searchLink>; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Sheahan+TP%22">Sheahan TP</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101519231%22">MBio</searchLink> [mBio] 2026 Jun 10; Vol. 17 (6), pp. e0007326. <i>Date of Electronic Publication: </i>2026 May 06.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101519231 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2150-7511 (Electronic) <i>NLM ISO Abbreviation: </i>mBio <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42089609
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1128/mbio.00073-26
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e0007326
    Titles:
      – TitleFull: Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Anderson-Daniels J
      – PersonEntity:
          Name:
            NameFull: Diefenbacher MV
      – PersonEntity:
          Name:
            NameFull: Yount BL
      – PersonEntity:
          Name:
            NameFull: Meganck RM
      – PersonEntity:
          Name:
            NameFull: Tse LV
      – PersonEntity:
          Name:
            NameFull: Burke KN
      – PersonEntity:
          Name:
            NameFull: Miranda HA
      – PersonEntity:
          Name:
            NameFull: Scobey DT
      – PersonEntity:
          Name:
            NameFull: Lu X
      – PersonEntity:
          Name:
            NameFull: Stevens L
      – PersonEntity:
          Name:
            NameFull: Dinnon KH 3rd
      – PersonEntity:
          Name:
            NameFull: Chapman NS
      – PersonEntity:
          Name:
            NameFull: Pajon C
      – PersonEntity:
          Name:
            NameFull: Powers JM
      – PersonEntity:
          Name:
            NameFull: Nguyen C
      – PersonEntity:
          Name:
            NameFull: Graham RL
      – PersonEntity:
          Name:
            NameFull: Heaton NS
      – PersonEntity:
          Name:
            NameFull: Baric RS
      – PersonEntity:
          Name:
            NameFull: Denison MR
      – PersonEntity:
          Name:
            NameFull: Sheahan TP
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 06
              Text: 2026 Jun 10
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2150-7511
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: MBio
              Type: main
ResultId 1