Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2.
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| Title: | Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2. |
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| Authors: | Anderson-Daniels J; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Diefenbacher MV; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Yount BL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Meganck RM; Department of Molecular Microbiology, Washington University in St Louis, St. Louis, Missouri, USA., Tse LV; Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, Missouri, USA., Burke KN; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Miranda HA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Scobey DT; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lu X; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Stevens L; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Dinnon KH 3rd; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Chapman NS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Pajon C; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Powers JM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Nguyen C; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Graham RL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Heaton NS; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Denison MR; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. |
| Source: | MBio [mBio] 2026 Jun 10; Vol. 17 (6), pp. e0007326. Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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