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High-Dose Sucralose Is Associated With Lacrimal Circadian Remodeling, Reduced Immunometabolic Signatures, and Reduced Tear Secretion.

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Title: High-Dose Sucralose Is Associated With Lacrimal Circadian Remodeling, Reduced Immunometabolic Signatures, and Reduced Tear Secretion.
Authors: Qi D; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China., Yang T; Department of Ophthalmology, People's Hospital of Henan University, Henan Provincial People's Hospital, Zhengzhou, Henan, China., Pei X; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China., Lu D; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China., Huang S; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China., Yang L; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China., Yang J; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China., Xuan S; Department of Ophthalmology, People's Hospital of Henan University, Henan Provincial People's Hospital, Zhengzhou, Henan, China., Ba M; Department of Ophthalmology, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan, China., Zhang W; Department of Ophthalmology, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan, China., Liu X; The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Yu S; Department of Ophthalmology, People's Hospital of Henan University, Henan Provincial People's Hospital, Zhengzhou, Henan, China., Li Z; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Source: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2026 May 01; Vol. 67 (5), pp. 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-Dose Sucralose Is Associated With Lacrimal Circadian Remodeling, Reduced Immunometabolic Signatures, and Reduced Tear Secretion.
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  Data: <searchLink fieldCode="AU" term="%22Qi+D%22">Qi D</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Yang+T%22">Yang T</searchLink>; Department of Ophthalmology, People's Hospital of Henan University, Henan Provincial People's Hospital, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Pei+X%22">Pei X</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Lu+D%22">Lu D</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Huang+S%22">Huang S</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Xuan+S%22">Xuan S</searchLink>; Department of Ophthalmology, People's Hospital of Henan University, Henan Provincial People's Hospital, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Ba+M%22">Ba M</searchLink>; Department of Ophthalmology, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Ophthalmology, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+S%22">Yu S</searchLink>; Department of Ophthalmology, People's Hospital of Henan University, Henan Provincial People's Hospital, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
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