Monte Carlo simulations identify suboptimal PK/PD target attainment with standard maribavir dosing.

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Title: Monte Carlo simulations identify suboptimal PK/PD target attainment with standard maribavir dosing.
Authors: Fromage Y; Inserm CIC 1435, CHU Dupuytren, Limoges, France.; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France., Sayadi H; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France., Labriffe M; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France., Codde C; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Infectious and Tropical Diseases Unit, CHU Dupuytren, Limoges, France., Alain S; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.; Microbiology Department, CHU Limoges, Limoges, France.; RESINFIT, UMR1092, Inserm, University of Limoges, CHU Limoges, Limoges, France.; National Reference Center for Herpesviruses, CHU Limoges, Limoges, France., Marquet P; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France., Woillard JB; Inserm CIC 1435, CHU Dupuytren, Limoges, France.; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France., Monchaud C; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.
Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2026 May 05; Vol. 81 (6).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Fromage+Y%22">Fromage Y</searchLink>; Inserm CIC 1435, CHU Dupuytren, Limoges, France.; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Sayadi+H%22">Sayadi H</searchLink>; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Labriffe+M%22">Labriffe M</searchLink>; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Codde+C%22">Codde C</searchLink>; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Infectious and Tropical Diseases Unit, CHU Dupuytren, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Alain+S%22">Alain S</searchLink>; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.; Microbiology Department, CHU Limoges, Limoges, France.; RESINFIT, UMR1092, Inserm, University of Limoges, CHU Limoges, Limoges, France.; National Reference Center for Herpesviruses, CHU Limoges, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Marquet+P%22">Marquet P</searchLink>; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Woillard+JB%22">Woillard JB</searchLink>; Inserm CIC 1435, CHU Dupuytren, Limoges, France.; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.<br /><searchLink fieldCode="AU" term="%22Monchaud+C%22">Monchaud C</searchLink>; Inserm UMR1248, Pharmacology & Transplantation, University of Limoges, Limoges, France.; Department of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, Limoges, France.; University Hospital Federation Survival Optimization in Organ Transplantation (FHU SUPORT), Limoges, France.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7513617 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2091 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203057453%22">03057453 </searchLink><i>NLM ISO Abbreviation: </i>J Antimicrob Chemother <i>Subsets: </i>MEDLINE
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        Value: 10.1093/jac/dkag153
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            – D: 05
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              Text: 2026 May 05
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              Y: 2026
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