Nasal steroids, irrigation, oral antibiotics, and subgroup targeting for effective management of acute sinusitis (NOSES): Protocol for a comparative effectiveness randomized controlled trial.
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| Title: | Nasal steroids, irrigation, oral antibiotics, and subgroup targeting for effective management of acute sinusitis (NOSES): Protocol for a comparative effectiveness randomized controlled trial. |
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| Authors: | Merenstein D; Clinical Coordinating Center, Department of Family Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America., Shara N; Data Coordinating Center, MedStar Health Research Institute, Columbia, Maryland, United States of America., Rabago DP; Department of Family and Community Medicine, Penn State College of Medicine, Hershey, Pennsylvania, United States of America., Tarn DM; Department of Family Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America., Barrett B; Department of Family Medicine and Community Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America., Krist AH; Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia, United States of America., Tong ST; Department of Family Medicine, University of Washington, Seattle, Washington, United States of America., Zgierska AE; Department of Family and Community Medicine, Penn State College of Medicine, Hershey, Pennsylvania, United States of America., Tan TP; Clinical Coordinating Center, Department of Family Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America., Smith KH; Clinical Coordinating Center, Department of Family Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America., Villalobos G; Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia, United States of America., Fencil CR; Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia, United States of America., Sanghavi KK; Data Coordinating Center, MedStar Health Research Institute, Columbia, Maryland, United States of America., Imam SJ; Data Coordinating Center, MedStar Health Research Institute, Columbia, Maryland, United States of America., Fernandez S; Data Coordinating Center, MedStar Health Research Institute, Columbia, Maryland, United States of America., Mete M; Data Coordinating Center, MedStar Health Research Institute, Columbia, Maryland, United States of America. |
| Source: | PloS one [PLoS One] 2026 May 06; Vol. 21 (5), pp. e0348522. Date of Electronic Publication: 2026 May 06 (Print Publication: 2026). |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0348522 |
