TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia.
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| Title: | TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia. |
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| Authors: | Priebe V; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.; Department of Molecular Mechanism of Disease, University of Zurich, Zurich, Switzerland., Galvan B; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Drakul A; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Margelisch N; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Aguadé-Gorgorió J; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA., Walavalkar K; Department of Molecular Mechanism of Disease, University of Zurich, Zurich, Switzerland., Huang Y; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Mikkola HKA; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA., Bornhauser B; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Santoro R; Department of Molecular Mechanism of Disease, University of Zurich, Zurich, Switzerland., Bourquin JP; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland. |
| Source: | Science advances [Sci Adv] 2026 May 08; Vol. 12 (19), pp. eadu3728. Date of Electronic Publication: 2026 May 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42090509 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Priebe+V%22">Priebe V</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.; Department of Molecular Mechanism of Disease, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Galvan+B%22">Galvan B</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Drakul+A%22">Drakul A</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Margelisch+N%22">Margelisch N</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Aguadé-Gorgorió+J%22">Aguadé-Gorgorió J</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Walavalkar+K%22">Walavalkar K</searchLink>; Department of Molecular Mechanism of Disease, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mikkola+HKA%22">Mikkola HKA</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bornhauser+B%22">Bornhauser B</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Santoro+R%22">Santoro R</searchLink>; Department of Molecular Mechanism of Disease, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bourquin+JP%22">Bourquin JP</searchLink>; Division of Oncology and Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2026 May 08; Vol. 12 (19), pp. eadu3728. <i>Date of Electronic Publication: </i>2026 May 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101653440 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2375-2548 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223752548%22">23752548 </searchLink><i>NLM ISO Abbreviation: </i>Sci Adv <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42090509 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/sciadv.adu3728 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eadu3728 Titles: – TitleFull: TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Priebe V – PersonEntity: Name: NameFull: Galvan B – PersonEntity: Name: NameFull: Drakul A – PersonEntity: Name: NameFull: Margelisch N – PersonEntity: Name: NameFull: Aguadé-Gorgorió J – PersonEntity: Name: NameFull: Walavalkar K – PersonEntity: Name: NameFull: Huang Y – PersonEntity: Name: NameFull: Mikkola HKA – PersonEntity: Name: NameFull: Bornhauser B – PersonEntity: Name: NameFull: Santoro R – PersonEntity: Name: NameFull: Bourquin JP IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 05 Text: 2026 May 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2375-2548 Numbering: – Type: volume Value: 12 – Type: issue Value: 19 Titles: – TitleFull: Science advances Type: main |
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