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Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies.

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Title: Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies.
Authors: Bernigaud C; Department of Dermatology, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil, France.; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris., Do-Pham G; Department of Internal Medicine, Centre Hospitalier Intercommunal de Créteil, Créteil, France., Guichard E; INSERM Centre d'Investigation Clinique (CIC) 1415, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, France., Beylot-Barry M; Department of Dermatology, INSERM Unité 1312, Centre Hospitalier Universitaire (CHU) and Université de Bordeaux, Bordeaux, France.; Center of Evidence of the French Society of Dermatology, Paris., Goujon E; Department of Dermatology, Hôpital William-Morey, Chalon-sur-Saône, France., Isnard C; Department of Dermatology, Hôpital Cochin-Port-Royal, AP-HP, Paris., Beneton N; Department of Dermatology, Centre Hospitalier Le Mans, Le Mans, France., Samimi M; Department of Dermatology, CHRU de Tours, Tours, France., Tedbirt B; Department of Dermatology, Hôpital Charles-Nicolle, CHU de Rouen, Rouen, France., Adamski H; Department of Dermatology, Hôpital Pontchaillou, CHU de Rennes, Rennes, France., Azib S; Department of Dermatology, Hôpital Claude-Huriez, CHU de Lille, Lille, France., Mahé E; Department of Dermatology, Hôpital Victor-Dupouy, Argenteuil, France., Michel C; Department of Dermatology, Groupe Hospitalier Mulhouse Sud-Alsace, Mulhouse, France., Perrot JL; Department of Dermatology, Hôpital Nord, CHU de Saint-Etienne, Saint-Etienne, France., Acquitter M; Department of Dermatology, Centre Hospitalier Cornouaille, Quimper, France., Bursztejn AC; Department of Dermatology, Hôpital Brabois, CHU de Nancy, Nancy, France., Chaby G; Center of Evidence of the French Society of Dermatology, Paris.; Department of Dermatology, Hôpital Sud, CHU d'Amiens, Amiens, France., Caux F; Department of Dermatology, Hôpital Avicenne, AP-HP, Bobigny, France., Passeron T; Department of Dermatology, Hôpital L'Archet 2, CHU de Nice, Nice, France., Vanhaecke C; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.; Department of Dermatology, Hôpital Robert-Debré, CHU de Reims, Reims, France., Mahé A; Department of Dermatology, Hôpitaux Civils de Colmar, Colmar, France., Leccia MT; Department of Dermatology, CHU de Grenoble, Grenoble, France., Barbarot S; Center of Evidence of the French Society of Dermatology, Paris.; Department of Dermatology, Hôtel-Dieu, CHU de Nantes, Nantes, France., Lenormand C; Department of Dermatology, Hôpital Civil, CHU de Strasbourg, Strasbourg, France., Aubin F; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.; Department of Dermatology, Centre Hospitalier Jean-Minjoz, CHU Besançon, Besançon, France., Foulet F; Department of Parasitology, Hôpital Henri-Mondor, AP-HP, Créteil, France., Grégoire L; Unité de Recherche Clinique, Hôpital Henri-Mondor, Créteil, France., Giraudeau B; INSERM Centre d'Investigation Clinique (CIC) 1415, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, France.; Université de Tours, Université de Nantes, INSERM Unité 1246, SPHERE (Methods for Patient-Centered Outcomes and Health Research), Tours, France., Chosidow O; Department of Dermatology, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil, France.; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.; Center of Evidence of the French Society of Dermatology, Paris.
Source: The New England journal of medicine [N Engl J Med] 2026 May 07; Vol. 394 (18), pp. 1814-1823.
Publication Type: Clinical Trial, Phase III; Equivalence Trial; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies.
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  Data: <searchLink fieldCode="AU" term="%22Bernigaud+C%22">Bernigaud C</searchLink>; Department of Dermatology, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil, France.; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.<br /><searchLink fieldCode="AU" term="%22Do-Pham+G%22">Do-Pham G</searchLink>; Department of Internal Medicine, Centre Hospitalier Intercommunal de Créteil, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Guichard+E%22">Guichard E</searchLink>; INSERM Centre d'Investigation Clinique (CIC) 1415, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, France.<br /><searchLink fieldCode="AU" term="%22Beylot-Barry+M%22">Beylot-Barry M</searchLink>; Department of Dermatology, INSERM Unité 1312, Centre Hospitalier Universitaire (CHU) and Université de Bordeaux, Bordeaux, France.; Center of Evidence of the French Society of Dermatology, Paris.<br /><searchLink fieldCode="AU" term="%22Goujon+E%22">Goujon E</searchLink>; Department of Dermatology, Hôpital William-Morey, Chalon-sur-Saône, France.<br /><searchLink fieldCode="AU" term="%22Isnard+C%22">Isnard C</searchLink>; Department of Dermatology, Hôpital Cochin-Port-Royal, AP-HP, Paris.<br /><searchLink fieldCode="AU" term="%22Beneton+N%22">Beneton N</searchLink>; Department of Dermatology, Centre Hospitalier Le Mans, Le Mans, France.<br /><searchLink fieldCode="AU" term="%22Samimi+M%22">Samimi M</searchLink>; Department of Dermatology, CHRU de Tours, Tours, France.<br /><searchLink fieldCode="AU" term="%22Tedbirt+B%22">Tedbirt B</searchLink>; Department of Dermatology, Hôpital Charles-Nicolle, CHU de Rouen, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Adamski+H%22">Adamski H</searchLink>; Department of Dermatology, Hôpital Pontchaillou, CHU de Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Azib+S%22">Azib S</searchLink>; Department of Dermatology, Hôpital Claude-Huriez, CHU de Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Mahé+E%22">Mahé E</searchLink>; Department of Dermatology, Hôpital Victor-Dupouy, Argenteuil, France.<br /><searchLink fieldCode="AU" term="%22Michel+C%22">Michel C</searchLink>; Department of Dermatology, Groupe Hospitalier Mulhouse Sud-Alsace, Mulhouse, France.<br /><searchLink fieldCode="AU" term="%22Perrot+JL%22">Perrot JL</searchLink>; Department of Dermatology, Hôpital Nord, CHU de Saint-Etienne, Saint-Etienne, France.<br /><searchLink fieldCode="AU" term="%22Acquitter+M%22">Acquitter M</searchLink>; Department of Dermatology, Centre Hospitalier Cornouaille, Quimper, France.<br /><searchLink fieldCode="AU" term="%22Bursztejn+AC%22">Bursztejn AC</searchLink>; Department of Dermatology, Hôpital Brabois, CHU de Nancy, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Chaby+G%22">Chaby G</searchLink>; Center of Evidence of the French Society of Dermatology, Paris.; Department of Dermatology, Hôpital Sud, CHU d'Amiens, Amiens, France.<br /><searchLink fieldCode="AU" term="%22Caux+F%22">Caux F</searchLink>; Department of Dermatology, Hôpital Avicenne, AP-HP, Bobigny, France.<br /><searchLink fieldCode="AU" term="%22Passeron+T%22">Passeron T</searchLink>; Department of Dermatology, Hôpital L'Archet 2, CHU de Nice, Nice, France.<br /><searchLink fieldCode="AU" term="%22Vanhaecke+C%22">Vanhaecke C</searchLink>; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.; Department of Dermatology, Hôpital Robert-Debré, CHU de Reims, Reims, France.<br /><searchLink fieldCode="AU" term="%22Mahé+A%22">Mahé A</searchLink>; Department of Dermatology, Hôpitaux Civils de Colmar, Colmar, France.<br /><searchLink fieldCode="AU" term="%22Leccia+MT%22">Leccia MT</searchLink>; Department of Dermatology, CHU de Grenoble, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Barbarot+S%22">Barbarot S</searchLink>; Center of Evidence of the French Society of Dermatology, Paris.; Department of Dermatology, Hôtel-Dieu, CHU de Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Lenormand+C%22">Lenormand C</searchLink>; Department of Dermatology, Hôpital Civil, CHU de Strasbourg, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Aubin+F%22">Aubin F</searchLink>; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.; Department of Dermatology, Centre Hospitalier Jean-Minjoz, CHU Besançon, Besançon, France.<br /><searchLink fieldCode="AU" term="%22Foulet+F%22">Foulet F</searchLink>; Department of Parasitology, Hôpital Henri-Mondor, AP-HP, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Grégoire+L%22">Grégoire L</searchLink>; Unité de Recherche Clinique, Hôpital Henri-Mondor, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Giraudeau+B%22">Giraudeau B</searchLink>; INSERM Centre d'Investigation Clinique (CIC) 1415, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, France.; Université de Tours, Université de Nantes, INSERM Unité 1246, SPHERE (Methods for Patient-Centered Outcomes and Health Research), Tours, France.<br /><searchLink fieldCode="AU" term="%22Chosidow+O%22">Chosidow O</searchLink>; Department of Dermatology, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil, France.; Groupe Infectiologie et Infections Sexuellement Transmissibles (GrIDIST) of the French Society of Dermatology, Paris.; Center of Evidence of the French Society of Dermatology, Paris.
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