Circulating 1-Methylnicotinamide Predicts Dupilumab Response in Adult Asthma: A Prediction Model.

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Title: Circulating 1-Methylnicotinamide Predicts Dupilumab Response in Adult Asthma: A Prediction Model.
Authors: Chae W; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Republic of Korea., An J; Department of Pulmonary, Allergy and Critical Care Medicine, College of Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul, Republic of Korea., Lee W; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim E; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee CE; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kwon HS; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Song WJ; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Cho YS; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee T; Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea., Ban GY; Department of Pulmonary, Allergy and Critical Care Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea., Lee BJ; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Park SY; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Division of Pulmonary, Allergy and Critical Care Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, South Korea., Nam YH; Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea., Park CS; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea., Kim JH; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea., Yang MS; Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea., Kim SH; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea., Park HK; Department of Internal Medicine, Pusan National University Hospital, Pusan National University College of Medicine, Busan, Korea., Choi JH; Department of Pulmonology and Allergy, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea., Kim S; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea., Kim MH; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea., Shim JS; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea., Ahn KM; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea., Park HK; Department of Allergy and Clinical Immunology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea., Jung JW; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea., Lee SM; Division of Pulmonology and Allergy, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea., Kwon JW; Department of Allergy and Clinical Immunology, Kangwon National University School of Medicine, Chuncheon, Korea., Hur GY; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea., Kim BK; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea., Moon JY; Division of Pulmonary and Allergy, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea., Sohn KH; Department of Internal Medicine, Kyung Hee University Medical Center, Seoul, Korea., Bhavsar PK; National Heart and Lung Institute, Imperial College London, London, UK., Adcock IM; National Heart and Lung Institute, Imperial College London, London, UK., Chung KF; National Heart and Lung Institute, Imperial College London, London, UK., Cho JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim TB; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Source: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2026 May 06. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article
Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8906443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2222 (Electronic) Linking ISSN: 09547894 NLM ISO Abbreviation: Clin Exp Allergy Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Chae+W%22">Chae W</searchLink>; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; Department of Pulmonary, Allergy and Critical Care Medicine, College of Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+W%22">Lee W</searchLink>; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+E%22">Kim E</searchLink>; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+CE%22">Lee CE</searchLink>; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+HS%22">Kwon HS</searchLink>; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Song+WJ%22">Song WJ</searchLink>; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YS%22">Cho YS</searchLink>; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+T%22">Lee T</searchLink>; Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.<br /><searchLink fieldCode="AU" term="%22Ban+GY%22">Ban GY</searchLink>; Department of Pulmonary, Allergy and Critical Care Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+BJ%22">Lee BJ</searchLink>; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SY%22">Park SY</searchLink>; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Division of Pulmonary, Allergy and Critical Care Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, South Korea.<br /><searchLink fieldCode="AU" term="%22Nam+YH%22">Nam YH</searchLink>; Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Park+CS%22">Park CS</searchLink>; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; 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Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Shim+JS%22">Shim JS</searchLink>; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+KM%22">Ahn KM</searchLink>; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Park+HK%22">Park HK</searchLink>; Department of Allergy and Clinical Immunology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+JW%22">Jung JW</searchLink>; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SM%22">Lee SM</searchLink>; Division of Pulmonology and Allergy, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+JW%22">Kwon JW</searchLink>; Department of Allergy and Clinical Immunology, Kangwon National University School of Medicine, Chuncheon, Korea.<br /><searchLink fieldCode="AU" term="%22Hur+GY%22">Hur GY</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BK%22">Kim BK</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Moon+JY%22">Moon JY</searchLink>; Division of Pulmonary and Allergy, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+KH%22">Sohn KH</searchLink>; Department of Internal Medicine, Kyung Hee University Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Bhavsar+PK%22">Bhavsar PK</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Adcock+IM%22">Adcock IM</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chung+KF%22">Chung KF</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cho+JY%22">Cho JY</searchLink>; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.; Kidney Research Institute, Seoul National University Medical Research Center, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TB%22">Kim TB</searchLink>; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
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