Evaluating the Utility and Constraints of the Competitive Counter Flow (CCF) Assay in OATP1B1 Substrate Profiling.
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| Title: | Evaluating the Utility and Constraints of the Competitive Counter Flow (CCF) Assay in OATP1B1 Substrate Profiling. |
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| Authors: | Mathialagan S; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., West MA; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Yamaguchi E; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Moulton HM; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Kapinos B; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Paryad Zanjani S; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Tess DA; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Cambridge, Massachusetts , USA., Kimoto E; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Varma MVS; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA., Yee SW; Pharmacokinetics, Dynamics and Metabolism, ADME Sciences, Pfizer Inc, Groton, Connecticut, USA. sookwah.yee@pfizer.com. |
| Source: | The AAPS journal [AAPS J] 2026 May 06; Vol. 28 (3). Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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