Runx1 and Runx2 act in concert to suppress Wnt/β-catenin-driven mammary tumourigenesis.

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Title: Runx1 and Runx2 act in concert to suppress Wnt/β-catenin-driven mammary tumourigenesis.
Authors: Riggio AI; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK.; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Sweeney K; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Shaw R; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Lawlor A; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Khan A; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Ferrari N; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Anand J; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Galbraith LC; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Gilroy K; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Bull C; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Young AL; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Athineos D; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Hall H; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Ghaffar F; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Hughes M; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Mitchell CA; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Mitchell L; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Nixon C; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Adams PD; Sanford Burnham Prebys Medical Discovery Institute, North Torrey Pines Road, La Jolla, CA, USA., Roberts EW; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Miller CJ; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK., Dunne PD; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK.; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Campbell KJ; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK., Cameron ER; School of Biodiversity One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK. Ewan.Cameron@glasgow.ac.uk., Blyth K; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, UK. Karen.Blyth@glasgow.ac.uk.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, UK. Karen.Blyth@glasgow.ac.uk.
Source: British journal of cancer [Br J Cancer] 2026 May 07. Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-1827
DOI:10.1038/s41416-026-03439-5