Efficacy and Safety of Rituximab Therapy to Sustain Remission in Young Children With Childhood Nephrotic Syndrome.

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Title: Efficacy and Safety of Rituximab Therapy to Sustain Remission in Young Children With Childhood Nephrotic Syndrome.
Authors: Chan EY; Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.; Paediatric Nephrology Centre, Hong Kong Children's Hospital, Hong Kong SAR.; Hong Kong Hub of Pediatric Excellence, The Chinese University of Hong Kong, Shatin, Hong Kong SAR., Au CT; Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.; Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada., Yu EL; Kowloon West Cluster Research Centre, Princess Margaret Hospital, Hong Kong SAR., Angeletti A; Department of Nephrology, Dialysis and Transplantation, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Laboratory of Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genova, Italy., Arslan Z; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.; University College London Great Ormond Street Institute of Child health, London, UK., Boyer O; Department of Pediatric Nephrology, Reference Center for Nephrotic Syndrome in Children and Adults, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Institut Imagine, Institut National de la Santé et de la Recherche Médicale U1163, Université Paris Cité, Paris, France., Chan CY; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Khoo Teck Puat National University Children's Medical Institute, National University Health System, Singapore., Colucci M; Laboratory of Nephrology, Translational Pediatrics and Clinical Genetics, Ospedale Pediatrico Bambino Gesù - Scientific Institute for Research and Health Care, Rome, Italy., Dorval G; Department of Pediatric Nephrology, Reference Center for Nephrotic Syndrome in Children and Adults, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Institut Imagine, Institut National de la Santé et de la Recherche Médicale U1163, Université Paris Cité, Paris, France., Dossier C; Pediatric Nephrology Department, Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France., Ghiggeri GM; Department of Nephrology, Dialysis and Transplantation, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Laboratory of Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genova, Italy., Hamada R; Department of Nephrology and Rheumatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan., Hogan J; Pediatric Nephrology Department, Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France., Ishikura K; Department of Pediatrics, Kitasato University School of Medicine, Kanagawa, Japan., Kamei K; Division of Nephrology and Rheumatology, National Center for Child Health and Development, Tokyo, Japan., Kemper MJ; Department of Pediatrics, Asklepios Medical School, Hamburg, Germany., Ma AL; Paediatric Nephrology Centre, Hong Kong Children's Hospital, Hong Kong SAR., Parekh RS; Departments of Medicine and Pediatrics, Women's College Hospital, Toronto, Ontario, Canada.; Division of Pediatric Nephrology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada., Radhakrishnan S; Division of Pediatric Nephrology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada., Robinson C; Division of Pediatric Nephrology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada., Shen Q; Department of Nephrology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China., Sinha R; Pediatric Nephrology Unit, Institute of Child Health, Kolkata, India., Subun C; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.; Division of Pediatric Nephrology, Phramongkutklao Hospital, Bangkok, Thailand., Teo S; Khoo Teck Puat National University Children's Medical Institute, National University Health System, Singapore., Vivarelli M; Laboratory of Nephrology, Translational Pediatrics and Clinical Genetics, Ospedale Pediatrico Bambino Gesù - Scientific Institute for Research and Health Care, Rome, Italy.; Division of Nephrology, Ospedale Pediatrico Bambino Gesù - Scientific Institute for Research and Health Care (IRCCS), Rome, Italy., Webb H; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK., Xu H; Department of Nephrology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China., Yamamura T; Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan., Yap HK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tullus K; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.; University College London Great Ormond Street Institute of Child health, London, UK.
Source: Kidney international reports [Kidney Int Rep] 2026 Apr 06; Vol. 11 (6), pp. 106526. Date of Electronic Publication: 2026 Apr 06 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101684752 Publication Model: eCollection Cited Medium: Internet ISSN: 2468-0249 (Electronic) Linking ISSN: 24680249 NLM ISO Abbreviation: Kidney Int Rep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and Safety of Rituximab Therapy to Sustain Remission in Young Children With Childhood Nephrotic Syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Chan+EY%22">Chan EY</searchLink>; Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.; Paediatric Nephrology Centre, Hong Kong Children's Hospital, Hong Kong SAR.; Hong Kong Hub of Pediatric Excellence, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.<br /><searchLink fieldCode="AU" term="%22Au+CT%22">Au CT</searchLink>; Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.; Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Yu+EL%22">Yu EL</searchLink>; Kowloon West Cluster Research Centre, Princess Margaret Hospital, Hong Kong SAR.<br /><searchLink fieldCode="AU" term="%22Angeletti+A%22">Angeletti A</searchLink>; Department of Nephrology, Dialysis and Transplantation, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Laboratory of Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Arslan+Z%22">Arslan Z</searchLink>; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.; University College London Great Ormond Street Institute of Child health, London, UK.<br /><searchLink fieldCode="AU" term="%22Boyer+O%22">Boyer O</searchLink>; Department of Pediatric Nephrology, Reference Center for Nephrotic Syndrome in Children and Adults, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Institut Imagine, Institut National de la Santé et de la Recherche Médicale U1163, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chan+CY%22">Chan CY</searchLink>; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Khoo Teck Puat National University Children's Medical Institute, National University Health System, Singapore.<br /><searchLink fieldCode="AU" term="%22Colucci+M%22">Colucci M</searchLink>; Laboratory of Nephrology, Translational Pediatrics and Clinical Genetics, Ospedale Pediatrico Bambino Gesù - Scientific Institute for Research and Health Care, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Dorval+G%22">Dorval G</searchLink>; Department of Pediatric Nephrology, Reference Center for Nephrotic Syndrome in Children and Adults, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Institut Imagine, Institut National de la Santé et de la Recherche Médicale U1163, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dossier+C%22">Dossier C</searchLink>; Pediatric Nephrology Department, Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ghiggeri+GM%22">Ghiggeri GM</searchLink>; Department of Nephrology, Dialysis and Transplantation, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Laboratory of Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Hamada+R%22">Hamada R</searchLink>; Department of Nephrology and Rheumatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hogan+J%22">Hogan J</searchLink>; Pediatric Nephrology Department, Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ishikura+K%22">Ishikura K</searchLink>; Department of Pediatrics, Kitasato University School of Medicine, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kamei+K%22">Kamei K</searchLink>; Division of Nephrology and Rheumatology, National Center for Child Health and Development, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kemper+MJ%22">Kemper MJ</searchLink>; Department of Pediatrics, Asklepios Medical School, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ma+AL%22">Ma AL</searchLink>; Paediatric Nephrology Centre, Hong Kong Children's Hospital, Hong Kong SAR.<br /><searchLink fieldCode="AU" term="%22Parekh+RS%22">Parekh RS</searchLink>; Departments of Medicine and Pediatrics, Women's College Hospital, Toronto, Ontario, Canada.; Division of Pediatric Nephrology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Radhakrishnan+S%22">Radhakrishnan S</searchLink>; Division of Pediatric Nephrology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Robinson+C%22">Robinson C</searchLink>; Division of Pediatric Nephrology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Shen+Q%22">Shen Q</searchLink>; Department of Nephrology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sinha+R%22">Sinha R</searchLink>; Pediatric Nephrology Unit, Institute of Child Health, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Subun+C%22">Subun C</searchLink>; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.; Division of Pediatric Nephrology, Phramongkutklao Hospital, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Teo+S%22">Teo S</searchLink>; Khoo Teck Puat National University Children's Medical Institute, National University Health System, Singapore.<br /><searchLink fieldCode="AU" term="%22Vivarelli+M%22">Vivarelli M</searchLink>; Laboratory of Nephrology, Translational Pediatrics and Clinical Genetics, Ospedale Pediatrico Bambino Gesù - Scientific Institute for Research and Health Care, Rome, Italy.; Division of Nephrology, Ospedale Pediatrico Bambino Gesù - Scientific Institute for Research and Health Care (IRCCS), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Webb+H%22">Webb H</searchLink>; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Nephrology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yamamura+T%22">Yamamura T</searchLink>; Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Yap+HK%22">Yap HK</searchLink>; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tullus+K%22">Tullus K</searchLink>; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK.; University College London Great Ormond Street Institute of Child health, London, UK.
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