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Overcoming T cell exhaustion and senescence in CAR T cell therapy for solid tumors.

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Title: Overcoming T cell exhaustion and senescence in CAR T cell therapy for solid tumors.
Authors: Pérez-Criado I; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain., Figols M; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain. mfigols@althaia.cat., Moya-Sevilla A; GRET and Toxicology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain., Bautista A; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain., Gómez-Díaz D; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain., Font A; Medical Oncology Department, Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain.; CARE Program, Germans Trias i Pujol Research Institute (IGTP), Camí de les Escoles, s/n, 08916, Badalona, Spain.; Badalona Applied Research Group in Oncology (B·ARGO), Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain., Martin-Liberal J; Medical Oncology Department, Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain.; CARE Program, Germans Trias i Pujol Research Institute (IGTP), Camí de les Escoles, s/n, 08916, Badalona, Spain.; Badalona Applied Research Group in Oncology (B·ARGO), Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain., Ruiz de Porras V; GRET and Toxicology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain. vruizdeporras@ub.edu.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2026 May 07. Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Overcoming T cell exhaustion and senescence in CAR T cell therapy for solid tumors.
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  Data: <searchLink fieldCode="AU" term="%22Pérez-Criado+I%22">Pérez-Criado I</searchLink>; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain.<br /><searchLink fieldCode="AU" term="%22Figols+M%22">Figols M</searchLink>; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain. mfigols@althaia.cat.<br /><searchLink fieldCode="AU" term="%22Moya-Sevilla+A%22">Moya-Sevilla A</searchLink>; GRET and Toxicology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bautista+A%22">Bautista A</searchLink>; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Díaz+D%22">Gómez-Díaz D</searchLink>; Medical Oncology Department, Althaia Xarxa Assistencial Universitària de Manresa, C/ Dr. Joan Soler, 1-3, 08243, Manresa, Spain.<br /><searchLink fieldCode="AU" term="%22Font+A%22">Font A</searchLink>; Medical Oncology Department, Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain.; CARE Program, Germans Trias i Pujol Research Institute (IGTP), Camí de les Escoles, s/n, 08916, Badalona, Spain.; Badalona Applied Research Group in Oncology (B·ARGO), Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Martin-Liberal+J%22">Martin-Liberal J</searchLink>; Medical Oncology Department, Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain.; CARE Program, Germans Trias i Pujol Research Institute (IGTP), Camí de les Escoles, s/n, 08916, Badalona, Spain.; Badalona Applied Research Group in Oncology (B·ARGO), Catalan Institute of Oncology, Camí de les Escoles, s/n, 08916, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz+de+Porras+V%22">Ruiz de Porras V</searchLink>; GRET and Toxicology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028, Barcelona, Spain. vruizdeporras@ub.edu.
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  Data: <searchLink fieldCode="JN" term="%22101247119%22">Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico</searchLink> [Clin Transl Oncol] 2026 May 07. <i>Date of Electronic Publication: </i>2026 May 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Italia%22">Springer Italia </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>101247119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1699-3055 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221699048X%22">1699048X </searchLink><i>NLM ISO Abbreviation: </i>Clin Transl Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12094-026-04383-9
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              Text: 2026 May 07
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