Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol.
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| Title: | Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol. |
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| Authors: | Ledingham D; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK david.ledingham1@nhs.net.; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Mills R; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK., Gibbs M; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK., Maynes M; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK., Pal A; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK., Iredale R; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK., Foster V; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK., Ong S; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK., Sathyanarayana S; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Jenkins A; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK., Nicholson C; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK., Hussain M; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK., Baker MR; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Pavese N; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Aarhus University Hospital Department of Nuclear Medicine & PET-Centre, Aarhus, Denmark. |
| Source: | BMJ open [BMJ Open] 2026 May 07; Vol. 16 (5), pp. e117391. Date of Electronic Publication: 2026 May 07. |
| Publication Type: | Journal Article; Observational Study |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42097654 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ledingham+D%22">Ledingham D</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK david.ledingham1@nhs.net.; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Mills+R%22">Mills R</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Gibbs+M%22">Gibbs M</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Maynes+M%22">Maynes M</searchLink>; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Pal+A%22">Pal A</searchLink>; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Iredale+R%22">Iredale R</searchLink>; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Foster+V%22">Foster V</searchLink>; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Ong+S%22">Ong S</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Sathyanarayana+S%22">Sathyanarayana S</searchLink>; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Jenkins+A%22">Jenkins A</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Nicholson+C%22">Nicholson C</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Hussain+M%22">Hussain M</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Baker+MR%22">Baker MR</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Pavese+N%22">Pavese N</searchLink>; Department of Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Aarhus University Hospital Department of Nuclear Medicine & PET-Centre, Aarhus, Denmark. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101552874%22">BMJ open</searchLink> [BMJ Open] 2026 May 07; Vol. 16 (5), pp. e117391. <i>Date of Electronic Publication: </i>2026 May 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Observational Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101552874 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2044-6055 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220446055%22">20446055 </searchLink><i>NLM ISO Abbreviation: </i>BMJ Open <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42097654 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1136/bmjopen-2026-117391 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e117391 Titles: – TitleFull: Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ledingham D – PersonEntity: Name: NameFull: Mills R – PersonEntity: Name: NameFull: Gibbs M – PersonEntity: Name: NameFull: Maynes M – PersonEntity: Name: NameFull: Pal A – PersonEntity: Name: NameFull: Iredale R – PersonEntity: Name: NameFull: Foster V – PersonEntity: Name: NameFull: Ong S – PersonEntity: Name: NameFull: Sathyanarayana S – PersonEntity: Name: NameFull: Jenkins A – PersonEntity: Name: NameFull: Nicholson C – PersonEntity: Name: NameFull: Hussain M – PersonEntity: Name: NameFull: Baker MR – PersonEntity: Name: NameFull: Pavese N IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 05 Text: 2026 May 07 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2044-6055 Numbering: – Type: volume Value: 16 – Type: issue Value: 5 Titles: – TitleFull: BMJ open Type: main |
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