Induction of stress granules alleviates programmed cell death induced by lysosomal damage during NK cell cryopreservation.

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Title: Induction of stress granules alleviates programmed cell death induced by lysosomal damage during NK cell cryopreservation.
Authors: Liu Y; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Liu X; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Wu G; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Wang X; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Yu K; Key Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin, China., Wang H; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Sun X; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Obstetrical Department, First Affiliated Hospital, Harbin Medical University, Harbin, China., An Z; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Xu H; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Department of Child Dental, First Affiliated Hospital, Harbin Medical University, Harbin, China., Zhao L; Department of Blood Transfusion, First Affiliated Hospital, Harbin Medical University, Harbin, China., Shi C; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China., Zheng SG; Department of Immunology, School of Cell and Gene Therapy, Songjiang Research Institute, Shanghai Songjiang District Central Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Huang M; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China. doctor_hml@163.com.; Obstetrical Department, First Affiliated Hospital, Harbin Medical University, Harbin, China. doctor_hml@163.com., Zhang Z; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China. zhirenz@163.com.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China. zhirenz@163.com.; Department of Cardiology and Pharmacy and Breast Cancer Surgery, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China. zhirenz@163.com., Wang Z; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China. zhenkunwang@hrbmu.edu.cn.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China. zhenkunwang@hrbmu.edu.cn.
Source: Cell death discovery [Cell Death Discov] 2026 May 07; Vol. 12 (1). Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
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  Data: Induction of stress granules alleviates programmed cell death induced by lysosomal damage during NK cell cryopreservation.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Wu+G%22">Wu G</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Yu+K%22">Yu K</searchLink>; Key Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Obstetrical Department, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22An+Z%22">An Z</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Department of Child Dental, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Blood Transfusion, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Shi+C%22">Shi C</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Zheng+SG%22">Zheng SG</searchLink>; Department of Immunology, School of Cell and Gene Therapy, Songjiang Research Institute, Shanghai Songjiang District Central Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China. doctor_hml@163.com.; Obstetrical Department, First Affiliated Hospital, Harbin Medical University, Harbin, China. doctor_hml@163.com.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China. zhirenz@163.com.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China. zhirenz@163.com.; Department of Cardiology and Pharmacy and Breast Cancer Surgery, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China. zhirenz@163.com.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; NHC Key Laboratory of Cell Transplantation, Harbin Medical University, Harbin, China. zhenkunwang@hrbmu.edu.cn.; Central Laboratory, First Affiliated Hospital, Harbin Medical University, Harbin, China. zhenkunwang@hrbmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2026 May 07; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 May 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41420-026-03149-0
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        Text: English
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      – TitleFull: Induction of stress granules alleviates programmed cell death induced by lysosomal damage during NK cell cryopreservation.
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              Text: 2026 May 07
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