SLX4IP limits replication stress globally and at ALT telomeres.
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| Title: | SLX4IP limits replication stress globally and at ALT telomeres. |
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| Authors: | Spindler J; Max Planck Institute for Biology of Ageing, Cologne, Germany., Pandolfo F; Max Planck Institute for Biology of Ageing, Cologne, Germany., Koch AE; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Piccirillo P; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Jordahl D; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA., Venkatesh N; Max Planck Institute for Biology of Ageing, Cologne, Germany., Suresh D; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Ylvisaker KR; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Jopkiewicz A; Max Planck Institute for Biology of Ageing, Cologne, Germany., Bihler J; Max Planck Institute for Biology of Ageing, Cologne, Germany., Buschbaum S; Max Planck Institute for Biology of Ageing, Cologne, Germany., Morgenstern M; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA., Overmyer KA; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA., Vincendeau E; Max Planck Institute for Biology of Ageing, Cologne, Germany., Coon JJ; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Wei PC; Brain Mosaicism and Tumorigenesis, German Cancer Research Center, Heidelberg, Germany.; Interdisciplinary Center for Neuroscience, Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Hänsel-Hertsch R; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine, University of Cologne, Cologne, Germany.; Institute of Human Genetics, University Hospital Cologne, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), Cologne, Germany., Mehta KPM; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. kmehta@wisc.edu., Panier S; Max Planck Institute for Biology of Ageing, Cologne, Germany. panier@age.mpg.de.; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), Cologne, Germany. panier@age.mpg.de.; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Cologne, Germany. panier@age.mpg.de. |
| Source: | The EMBO journal [EMBO J] 2026 Jun; Vol. 45 (12), pp. 4176-4219. Date of Electronic Publication: 2026 May 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42098304 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: SLX4IP limits replication stress globally and at ALT telomeres. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Spindler+J%22">Spindler J</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Pandolfo+F%22">Pandolfo F</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Koch+AE%22">Koch AE</searchLink>; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Piccirillo+P%22">Piccirillo P</searchLink>; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Jordahl+D%22">Jordahl D</searchLink>; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Venkatesh+N%22">Venkatesh N</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Suresh+D%22">Suresh D</searchLink>; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ylvisaker+KR%22">Ylvisaker KR</searchLink>; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Jopkiewicz+A%22">Jopkiewicz A</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Bihler+J%22">Bihler J</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Buschbaum+S%22">Buschbaum S</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Morgenstern+M%22">Morgenstern M</searchLink>; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Overmyer+KA%22">Overmyer KA</searchLink>; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Vincendeau+E%22">Vincendeau E</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Coon+JJ%22">Coon JJ</searchLink>; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Wei+PC%22">Wei PC</searchLink>; Brain Mosaicism and Tumorigenesis, German Cancer Research Center, Heidelberg, Germany.; Interdisciplinary Center for Neuroscience, Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hänsel-Hertsch+R%22">Hänsel-Hertsch R</searchLink>; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine, University of Cologne, Cologne, Germany.; Institute of Human Genetics, University Hospital Cologne, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Mehta+KPM%22">Mehta KPM</searchLink>; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. kmehta@wisc.edu.<br /><searchLink fieldCode="AU" term="%22Panier+S%22">Panier S</searchLink>; Max Planck Institute for Biology of Ageing, Cologne, Germany. panier@age.mpg.de.; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), Cologne, Germany. panier@age.mpg.de.; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Cologne, Germany. panier@age.mpg.de. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2026 Jun; Vol. 45 (12), pp. 4176-4219. <i>Date of Electronic Publication: </i>2026 May 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8208664 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2075 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202614189%22">02614189 </searchLink><i>NLM ISO Abbreviation: </i>EMBO J <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42098304 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s44318-026-00790-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 4176 Titles: – TitleFull: SLX4IP limits replication stress globally and at ALT telomeres. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Spindler J – PersonEntity: Name: NameFull: Pandolfo F – PersonEntity: Name: NameFull: Koch AE – PersonEntity: Name: NameFull: Piccirillo P – PersonEntity: Name: NameFull: Jordahl D – PersonEntity: Name: NameFull: Venkatesh N – PersonEntity: Name: NameFull: Suresh D – PersonEntity: Name: NameFull: Ylvisaker KR – PersonEntity: Name: NameFull: Jopkiewicz A – PersonEntity: Name: NameFull: Bihler J – PersonEntity: Name: NameFull: Buschbaum S – PersonEntity: Name: NameFull: Morgenstern M – PersonEntity: Name: NameFull: Overmyer KA – PersonEntity: Name: NameFull: Vincendeau E – PersonEntity: Name: NameFull: Coon JJ – PersonEntity: Name: NameFull: Wei PC – PersonEntity: Name: NameFull: Hänsel-Hertsch R – PersonEntity: Name: NameFull: Mehta KPM – PersonEntity: Name: NameFull: Panier S IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1460-2075 Numbering: – Type: volume Value: 45 – Type: issue Value: 12 Titles: – TitleFull: The EMBO journal Type: main |
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