View in EDS

Symptom-guided approach to central nervous system complications in allogeneic hematopoietic cell transplant recipients: Best practice recommendations from the EBMT Practice Harmonisation and Guidelines committee.

Saved in:
Bibliographic Details
Title: Symptom-guided approach to central nervous system complications in allogeneic hematopoietic cell transplant recipients: Best practice recommendations from the EBMT Practice Harmonisation and Guidelines committee.
Authors: Velasco R; Department of Neurology, Neuro-oncology Unit, Institut Català d'Oncologia - Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain. rvelascof@bellvitgehospital.cat.; Department of Cell Biology, Physiology, and Immunology, Universitat Autònoma de Barcelona, Bellaterra, & CIBERNED, Barcelona, Spain. rvelascof@bellvitgehospital.cat.; Complications Working Party, EBMT, Paris, France. rvelascof@bellvitgehospital.cat., Schmidt-Hieber M; Clinic for Oncology, Hematology, Pneumology, Nephrology and Diabetology, Medical University Lausitz - Carl Thiem (MUL-CT), Cottbus, Germany.; Infectious Diseases Working Party, EBMT, Leiden, Netherlands., Penack O; Complications Working Party, EBMT, Paris, France.; Department of Hematology, Oncology and Tumorimmunology, Charite University Hospital, Free University of Berlin and Humboldt University of Berlin, Berlin, Germany.; National Center for Tumor Diseases, Berlin, Germany., Averbuch D; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.; Hadassah Medical Center, Jerusalem, Israel., Balaguer-Roselló A; Department of Hematology, Hospital Universitari I Politècnic la Fe, València, Spain., Baccelli F; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Pediatric Hematology and Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Bataller L; Department of Neurology, Instituto Valenciano de Oncología, Valencia, Spain.; Department of Medicine, University of Valencia, Valencia, Spain., Cesaro S; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Pediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy., Briani C; Department of Neurosciences, Neurology Unit, University of Padova, Padova, Italy., de la Cámara R; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Hematology Department, Hospital de la Princesa, Madrid, Spain., Huehnchen P; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department for Neurology with Experimental Neurology, Berlin, Germany.; Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, NeuroCure Cluster of Excellence, Berlin, Germany., de Silva T; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK., Mussetti A; Complications Working Party, EBMT, Paris, France.; Clinical Hematology Department, Institut Català d'Oncologia, Hospitalet de Llobregat, Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain., Ljungman P; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Dept. of Cellular Therapy and Allogeneic Stem Cell Transplantation, Comprehensive Cancer Center, and Dept. of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine Huddinge, Karolinska Institutet (KI), Stockholm, Sweden., Perić Z; Complications Working Party, EBMT, Paris, France.; Department of Hematology, University Hospital Centre Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia., Mikulska M; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Division of Infectious Diseases, Department of Health Sciences (DISSAL), University of Genova, Genova, Italy.; IRCCS Azienda Ospedaliera Metropolitana, Genova, Italy., Polushin A; R.M. Gorbacheva Research Institute, Pavlov University, St, Petersburg, Russia., Navarro Ortega D; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain.; CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.; Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain., Pons-Escoda A; Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain.; Department of Neuro-Radiology, Neuro-oncology Unit, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Neofytos D; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Division of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland., Schoemans H; Complications Working Party, EBMT, Paris, France.; Department of Hematology, University Hospitals Leuven, Leuven, Belgium.; Department of Public Health and Primary Care, ACCENT VV, KU Leuven - University of Leuven, Leuven, Belgium., Piñana JL; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Department of Hematology. Hospital Clínico Universitario of Valencia, Valencia, Spain.; INCLIVA, Biomedical Research Institute, Valencia, Spain., Onida F; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Haematology and BMT Unit, ASST Fatebenefratelli-Sacco, Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Ruggeri A; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Cellular Therapy & Immunobiology Working Party, EBMT, Leiden, Netherlands.; Hematology and BMT Unit, San Raffaele Scientific Institute, Milan, Italy., Sanchez-Ortega I; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Medical Officer, EBMT, Executive Office, EBMT, Barcelona, Spain., Yakoub-Agha I; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Centre Hospitalier Universitaire de Lille, University of Lille, INSERM U1286, Lille, France., Styczynski J; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Department of Pediatric Hematology, Oncology, Immunology and Transplantology, Collegium Medicum, Nicolaus Copernicus University Torun, University Hospital, Bydgoszcz, Poland.
Source: Bone marrow transplantation [Bone Marrow Transplant] 2026 Jul; Vol. 61 (7), pp. 805-815. Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article; Practice Guideline; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8702459 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5365 (Electronic) Linking ISSN: 02683369 NLM ISO Abbreviation: Bone Marrow Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42098382
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Symptom-guided approach to central nervous system complications in allogeneic hematopoietic cell transplant recipients: Best practice recommendations from the EBMT Practice Harmonisation and Guidelines committee.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Velasco+R%22">Velasco R</searchLink>; Department of Neurology, Neuro-oncology Unit, Institut Català d'Oncologia - Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain. rvelascof@bellvitgehospital.cat.; Department of Cell Biology, Physiology, and Immunology, Universitat Autònoma de Barcelona, Bellaterra, & CIBERNED, Barcelona, Spain. rvelascof@bellvitgehospital.cat.; Complications Working Party, EBMT, Paris, France. rvelascof@bellvitgehospital.cat.<br /><searchLink fieldCode="AU" term="%22Schmidt-Hieber+M%22">Schmidt-Hieber M</searchLink>; Clinic for Oncology, Hematology, Pneumology, Nephrology and Diabetology, Medical University Lausitz - Carl Thiem (MUL-CT), Cottbus, Germany.; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Penack+O%22">Penack O</searchLink>; Complications Working Party, EBMT, Paris, France.; Department of Hematology, Oncology and Tumorimmunology, Charite University Hospital, Free University of Berlin and Humboldt University of Berlin, Berlin, Germany.; National Center for Tumor Diseases, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Averbuch+D%22">Averbuch D</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.; Hadassah Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Balaguer-Roselló+A%22">Balaguer-Roselló A</searchLink>; Department of Hematology, Hospital Universitari I Politècnic la Fe, València, Spain.<br /><searchLink fieldCode="AU" term="%22Baccelli+F%22">Baccelli F</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Pediatric Hematology and Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Bataller+L%22">Bataller L</searchLink>; Department of Neurology, Instituto Valenciano de Oncología, Valencia, Spain.; Department of Medicine, University of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Cesaro+S%22">Cesaro S</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Pediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Briani+C%22">Briani C</searchLink>; Department of Neurosciences, Neurology Unit, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22de+la+Cámara+R%22">de la Cámara R</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Hematology Department, Hospital de la Princesa, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Huehnchen+P%22">Huehnchen P</searchLink>; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department for Neurology with Experimental Neurology, Berlin, Germany.; Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, NeuroCure Cluster of Excellence, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22de+Silva+T%22">de Silva T</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Mussetti+A%22">Mussetti A</searchLink>; Complications Working Party, EBMT, Paris, France.; Clinical Hematology Department, Institut Català d'Oncologia, Hospitalet de Llobregat, Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ljungman+P%22">Ljungman P</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Dept. of Cellular Therapy and Allogeneic Stem Cell Transplantation, Comprehensive Cancer Center, and Dept. of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine Huddinge, Karolinska Institutet (KI), Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Perić+Z%22">Perić Z</searchLink>; Complications Working Party, EBMT, Paris, France.; Department of Hematology, University Hospital Centre Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.<br /><searchLink fieldCode="AU" term="%22Mikulska+M%22">Mikulska M</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Division of Infectious Diseases, Department of Health Sciences (DISSAL), University of Genova, Genova, Italy.; IRCCS Azienda Ospedaliera Metropolitana, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Polushin+A%22">Polushin A</searchLink>; R.M. Gorbacheva Research Institute, Pavlov University, St, Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Navarro+Ortega+D%22">Navarro Ortega D</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain.; CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.; Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Pons-Escoda+A%22">Pons-Escoda A</searchLink>; Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain.; Department of Neuro-Radiology, Neuro-oncology Unit, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Neofytos+D%22">Neofytos D</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Division of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schoemans+H%22">Schoemans H</searchLink>; Complications Working Party, EBMT, Paris, France.; Department of Hematology, University Hospitals Leuven, Leuven, Belgium.; Department of Public Health and Primary Care, ACCENT VV, KU Leuven - University of Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Piñana+JL%22">Piñana JL</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Department of Hematology. Hospital Clínico Universitario of Valencia, Valencia, Spain.; INCLIVA, Biomedical Research Institute, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Onida+F%22">Onida F</searchLink>; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Haematology and BMT Unit, ASST Fatebenefratelli-Sacco, Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ruggeri+A%22">Ruggeri A</searchLink>; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Cellular Therapy & Immunobiology Working Party, EBMT, Leiden, Netherlands.; Hematology and BMT Unit, San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sanchez-Ortega+I%22">Sanchez-Ortega I</searchLink>; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Medical Officer, EBMT, Executive Office, EBMT, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Yakoub-Agha+I%22">Yakoub-Agha I</searchLink>; Practice Harmonisation and Guidelines Committee, EBMT, Barcelona, Spain.; Centre Hospitalier Universitaire de Lille, University of Lille, INSERM U1286, Lille, France.<br /><searchLink fieldCode="AU" term="%22Styczynski+J%22">Styczynski J</searchLink>; Infectious Diseases Working Party, EBMT, Leiden, Netherlands.; Department of Pediatric Hematology, Oncology, Immunology and Transplantology, Collegium Medicum, Nicolaus Copernicus University Torun, University Hospital, Bydgoszcz, Poland.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228702459%22">Bone marrow transplantation</searchLink> [Bone Marrow Transplant] 2026 Jul; Vol. 61 (7), pp. 805-815. <i>Date of Electronic Publication: </i>2026 May 07.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Practice Guideline; Review
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8702459 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5365 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202683369%22">02683369 </searchLink><i>NLM ISO Abbreviation: </i>Bone Marrow Transplant <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42098382
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41409-026-02866-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 805
    Titles:
      – TitleFull: Symptom-guided approach to central nervous system complications in allogeneic hematopoietic cell transplant recipients: Best practice recommendations from the EBMT Practice Harmonisation and Guidelines committee.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Velasco R
      – PersonEntity:
          Name:
            NameFull: Schmidt-Hieber M
      – PersonEntity:
          Name:
            NameFull: Penack O
      – PersonEntity:
          Name:
            NameFull: Averbuch D
      – PersonEntity:
          Name:
            NameFull: Balaguer-Roselló A
      – PersonEntity:
          Name:
            NameFull: Baccelli F
      – PersonEntity:
          Name:
            NameFull: Bataller L
      – PersonEntity:
          Name:
            NameFull: Cesaro S
      – PersonEntity:
          Name:
            NameFull: Briani C
      – PersonEntity:
          Name:
            NameFull: de la Cámara R
      – PersonEntity:
          Name:
            NameFull: Huehnchen P
      – PersonEntity:
          Name:
            NameFull: de Silva T
      – PersonEntity:
          Name:
            NameFull: Mussetti A
      – PersonEntity:
          Name:
            NameFull: Ljungman P
      – PersonEntity:
          Name:
            NameFull: Perić Z
      – PersonEntity:
          Name:
            NameFull: Mikulska M
      – PersonEntity:
          Name:
            NameFull: Polushin A
      – PersonEntity:
          Name:
            NameFull: Navarro Ortega D
      – PersonEntity:
          Name:
            NameFull: Pons-Escoda A
      – PersonEntity:
          Name:
            NameFull: Neofytos D
      – PersonEntity:
          Name:
            NameFull: Schoemans H
      – PersonEntity:
          Name:
            NameFull: Piñana JL
      – PersonEntity:
          Name:
            NameFull: Onida F
      – PersonEntity:
          Name:
            NameFull: Ruggeri A
      – PersonEntity:
          Name:
            NameFull: Sanchez-Ortega I
      – PersonEntity:
          Name:
            NameFull: Yakoub-Agha I
      – PersonEntity:
          Name:
            NameFull: Styczynski J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5365
          Numbering:
            – Type: volume
              Value: 61
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Bone marrow transplantation
              Type: main
ResultId 1