Nudging implementation of low tidal volume ventilation: a stepped wedge, cluster randomized trial.

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Title: Nudging implementation of low tidal volume ventilation: a stepped wedge, cluster randomized trial.
Authors: Kerlin MP; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA. prasadm@pennmedicine.upenn.edu.; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. prasadm@pennmedicine.upenn.edu.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA. prasadm@pennmedicine.upenn.edu., Harhay MO; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA, USA., Li F; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA., Small DS; Department of Statistics, The Wharton School at the University of Pennsylvania, Philadelphia, PA, USA., Lu Y; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Wang W; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Fuchs BD; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA., Mikkelsen ME; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Anschutz Medical Campus, Denver, CO, USA., Tran T; Continuous Improvement and Innovation, Seattle Children's Hospital, Seattle, WA, USA., Belk A; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Silvestri JA; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Center for Health Incentives and Behavioral Economics (CHIBE), University of Pennsylvania, Philadelphia, PA, USA., Klaiman T; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Center for Health Incentives and Behavioral Economics (CHIBE), University of Pennsylvania, Philadelphia, PA, USA., Scott S; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Levy E; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA., Sjoding MW; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Kohn R; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA.; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA., Roberts KJ; Department of Cardiovascular and Pulmonary Sciences, College of Health Professions, Thomas Jefferson University, Philadelphia, PA, USA., Beidas RS; Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Halpern SD; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA.; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medical Ethics and Health Policy, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Source: Implementation science : IS [Implement Sci] 2026 May 07; Vol. 21 (1). Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258411 Publication Model: Electronic Cited Medium: Internet ISSN: 1748-5908 (Electronic) Linking ISSN: 17485908 NLM ISO Abbreviation: Implement Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kerlin+MP%22">Kerlin MP</searchLink>; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA. prasadm@pennmedicine.upenn.edu.; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. prasadm@pennmedicine.upenn.edu.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA. prasadm@pennmedicine.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Harhay+MO%22">Harhay MO</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Small+DS%22">Small DS</searchLink>; Department of Statistics, The Wharton School at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fuchs+BD%22">Fuchs BD</searchLink>; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Mikkelsen+ME%22">Mikkelsen ME</searchLink>; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Anschutz Medical Campus, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Tran+T%22">Tran T</searchLink>; Continuous Improvement and Innovation, Seattle Children's Hospital, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Belk+A%22">Belk A</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Silvestri+JA%22">Silvestri JA</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Center for Health Incentives and Behavioral Economics (CHIBE), University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Klaiman+T%22">Klaiman T</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Center for Health Incentives and Behavioral Economics (CHIBE), University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Scott+S%22">Scott S</searchLink>; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Levy+E%22">Levy E</searchLink>; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Sjoding+MW%22">Sjoding MW</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kohn+R%22">Kohn R</searchLink>; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA.; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Roberts+KJ%22">Roberts KJ</searchLink>; Department of Cardiovascular and Pulmonary Sciences, College of Health Professions, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Beidas+RS%22">Beidas RS</searchLink>; Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Halpern+SD%22">Halpern SD</searchLink>; Pulmonary, Critical Care and Allergy Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Perelman Center for Advanced Medicine, 627 South Pavilion, Philadelphia, PA, 19104, USA.; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medical Ethics and Health Policy, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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