3D-printed dictamni-calcium silicate scaffolds modulate the osteoimmune microenvironment and enhance macrophage-derived exosomal miR-21 signaling in vascularized bone regeneration.
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| Title: | 3D-printed dictamni-calcium silicate scaffolds modulate the osteoimmune microenvironment and enhance macrophage-derived exosomal miR-21 signaling in vascularized bone regeneration. |
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| Authors: | Ho CC; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan.; High Performance Materials Institute for x-Dimensional Printing, Asia University, Taichung, 41354, Taiwan., Hsu TT; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan., Lin YH; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan., Kuo TY; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan., Chen CY; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan., Hu SH; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, 300044, Taiwan., Huang JT; Department of Orthopedics, Asia University Hospital, Taichung, 41354, Taiwan., Lin TL; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, 406040, Taiwan. alilin422@yahoo.com.tw.; Department of Orthopedics, China Medical University Hospital, Taichung, 404332, Taiwan. alilin422@yahoo.com.tw., Cho DY; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan. dycho1212@gmail.com.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan. dycho1212@gmail.com.; Department of Neurosurgery, China Medical University Hospital, Taichung, 404332, Taiwan. dycho1212@gmail.com., Shie MY; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan. eric@mail.cmu.edu.tw.; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan. eric@mail.cmu.edu.tw.; Department of Biomedical Engineering, China Medical University, Taichung, 406040, Taiwan. eric@mail.cmu.edu.tw. |
| Source: | Journal of nanobiotechnology [J Nanobiotechnology] 2026 May 07; Vol. 24 (1). Date of Electronic Publication: 2026 May 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42098777 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: 3D-printed dictamni-calcium silicate scaffolds modulate the osteoimmune microenvironment and enhance macrophage-derived exosomal miR-21 signaling in vascularized bone regeneration. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ho+CC%22">Ho CC</searchLink>; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan.; High Performance Materials Institute for x-Dimensional Printing, Asia University, Taichung, 41354, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+TT%22">Hsu TT</searchLink>; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YH%22">Lin YH</searchLink>; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+TY%22">Kuo TY</searchLink>; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CY%22">Chen CY</searchLink>; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hu+SH%22">Hu SH</searchLink>; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, 300044, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+JT%22">Huang JT</searchLink>; Department of Orthopedics, Asia University Hospital, Taichung, 41354, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+TL%22">Lin TL</searchLink>; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, 406040, Taiwan. alilin422@yahoo.com.tw.; Department of Orthopedics, China Medical University Hospital, Taichung, 404332, Taiwan. alilin422@yahoo.com.tw.<br /><searchLink fieldCode="AU" term="%22Cho+DY%22">Cho DY</searchLink>; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan. dycho1212@gmail.com.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan. dycho1212@gmail.com.; Department of Neurosurgery, China Medical University Hospital, Taichung, 404332, Taiwan. dycho1212@gmail.com.<br /><searchLink fieldCode="AU" term="%22Shie+MY%22">Shie MY</searchLink>; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan. eric@mail.cmu.edu.tw.; Xenotransplantation Translational Research Center, China Medical University Hospital, Taichung, 404327, Taiwan. eric@mail.cmu.edu.tw.; Department of Biomedical Engineering, China Medical University, Taichung, 406040, Taiwan. eric@mail.cmu.edu.tw. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2026 May 07; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 May 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42098777 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12951-026-04507-x Languages: – Code: eng Text: English Titles: – TitleFull: 3D-printed dictamni-calcium silicate scaffolds modulate the osteoimmune microenvironment and enhance macrophage-derived exosomal miR-21 signaling in vascularized bone regeneration. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ho CC – PersonEntity: Name: NameFull: Hsu TT – PersonEntity: Name: NameFull: Lin YH – PersonEntity: Name: NameFull: Kuo TY – PersonEntity: Name: NameFull: Chen CY – PersonEntity: Name: NameFull: Hu SH – PersonEntity: Name: NameFull: Huang JT – PersonEntity: Name: NameFull: Lin TL – PersonEntity: Name: NameFull: Cho DY – PersonEntity: Name: NameFull: Shie MY IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 05 Text: 2026 May 07 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1477-3155 Numbering: – Type: volume Value: 24 – Type: issue Value: 1 Titles: – TitleFull: Journal of nanobiotechnology Type: main |
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