Early syndecan-4 upregulation predicts cognitive and pathological trajectories in Alzheimer disease.
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| Title: | Early syndecan-4 upregulation predicts cognitive and pathological trajectories in Alzheimer disease. |
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| Authors: | Tarawneh R; Department of Neurology, Saint Louis University, 1008 S Spring Ave, St Louis, MO, 63110, USA. Rawan.Tarawneh@health.slu.edu., Moulder KL; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA., Topouza DG; Olink Proteomics, Part of Thermo-Fisher Scientific, Boston, MA, 02453, USA., Kar A; Olink Proteomics, Part of Thermo-Fisher Scientific, Boston, MA, 02453, USA., Qian HT; Olink Proteomics, Part of Thermo-Fisher Scientific, Boston, MA, 02453, USA., Pankratz VS; Department of Internal Medicine, Division of Epidemiology, Biostatistics, and Preventive Medicine, University of New Mexico, Albuquerque, NM, 87110, USA., Timsina J; Department of Psychiatry, Washington University in St Louis, St Louis, MO, 63110, USA.; Neuro-Genomics and Informatics Center, Washington University in St Louis, St Louis, MO, 63110, USA., Franklin EE; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Department of Pathology and Immunology, Washington University in St Louis, St Louis, MO, 63110, USA., Schindler SE; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, 63110, USA., Perrin RJ; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Department of Pathology and Immunology, Washington University in St Louis, St Louis, MO, 63110, USA.; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, 63110, USA., Ances BM; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, 63110, USA.; Department of Radiology, Washington University in St Louis, St Louis, MO, 63110, USA., Benzinger TLS; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, 63110, USA.; Department of Radiology, Washington University in St Louis, St Louis, MO, 63110, USA., Hassenstab J; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Department of Psychological and Brain Sciences, Washington University in St Louis, St Louis, MO, 63110, USA., Morris JC; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA., Holtzman DM; Department of Neurology, Washington University in St Louis, St Louis, MO, 63110, USA.; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, 63110, USA., Cruchaga C; Knight Washington University Alzheimer Disease Research Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Department of Psychiatry, Washington University in St Louis, St Louis, MO, 63110, USA.; Neuro-Genomics and Informatics Center, Washington University in St Louis, St Louis, MO, 63110, USA.; Hope Center for Neurological Disorders, Washington University in St Louis, St Louis, MO, 63110, USA. |
| Source: | Alzheimer's research & therapy [Alzheimers Res Ther] 2026 May 07; Vol. 18 (1). Date of Electronic Publication: 2026 May 07. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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