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Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibition in PIK3CA mutant breast cancer.

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Bibliographic Details
Title: Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibition in PIK3CA mutant breast cancer.
Authors: Lero MW, Morgan JS, Card MA, Zhu LJ, Li J, Li R, Bui QT, Mohlmann E, Shaw LM
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 28. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42099435
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
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  Data: Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibition in PIK3CA mutant breast cancer.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Lero+MW%22">Lero MW</searchLink><br /><searchLink fieldCode="AU" term="%22Morgan+JS%22">Morgan JS</searchLink><br /><searchLink fieldCode="AU" term="%22Card+MA%22">Card MA</searchLink><br /><searchLink fieldCode="AU" term="%22Zhu+LJ%22">Zhu LJ</searchLink><br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink><br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink><br /><searchLink fieldCode="AU" term="%22Bui+QT%22">Bui QT</searchLink><br /><searchLink fieldCode="AU" term="%22Mohlmann+E%22">Mohlmann E</searchLink><br /><searchLink fieldCode="AU" term="%22Shaw+LM%22">Shaw LM</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Apr 28. <i>Date of Electronic Publication: </i>2026 Apr 28.
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  Label: Publication Type
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  Data: Journal Article; Preprint
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42099435
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.64898/2026.04.24.720709
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibition in PIK3CA mutant breast cancer.
        Type: main
  BibRelationships:
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      – PersonEntity:
          Name:
            NameFull: Lero MW
      – PersonEntity:
          Name:
            NameFull: Morgan JS
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            NameFull: Card MA
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          Name:
            NameFull: Zhu LJ
      – PersonEntity:
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            NameFull: Li J
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            NameFull: Li R
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            NameFull: Bui QT
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            NameFull: Mohlmann E
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            NameFull: Shaw LM
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          Dates:
            – D: 28
              M: 04
              Text: 2026 Apr 28
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
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