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Discontinuing Long-Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

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Title: Discontinuing Long-Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?
Authors: Lu KH; Department of Orthopedics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Lin RC; Department of Orthopedics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Chang IL; Department of Orthopaedic Surgery, Changhua Christian Hospital, Changhua, Taiwan., Fu SH; Department of Orthopedics, National Taiwan University Hospital Yun-Lin Branch, Douliu, Taiwan., Tsai MY; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan., Yang SF; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2026 Aug; Vol. 120 (2), pp. 334-344. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Discontinuing Long-Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?
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  Data: <searchLink fieldCode="AU" term="%22Lu+KH%22">Lu KH</searchLink>; Department of Orthopedics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+RC%22">Lin RC</searchLink>; Department of Orthopedics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+IL%22">Chang IL</searchLink>; Department of Orthopaedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fu+SH%22">Fu SH</searchLink>; Department of Orthopedics, National Taiwan University Hospital Yun-Lin Branch, Douliu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+MY%22">Tsai MY</searchLink>; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+SF%22">Yang SF</searchLink>; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%220372741%22">Clinical pharmacology and therapeutics</searchLink> [Clin Pharmacol Ther] 2026 Aug; Vol. 120 (2), pp. 334-344. <i>Date of Electronic Publication: </i>2026 May 08.
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        Value: 10.1002/cpt.70323
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        Text: English
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      – TitleFull: Discontinuing Long-Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?
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              Text: 2026 Aug
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