Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation.
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| Title: | Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation. |
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| Authors: | Saha G; Laboratory of Molecular and Mechanistic Cell Signaling, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Anchi P; Laboratory of Molecular and Mechanistic Cell Signaling, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Wang R; Laboratory of Molecular and Mechanistic Cell Signaling, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Biondo A; Laboratory of Stem Cell Regenerative Research, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Meyer S; Laboratory of Molecular and Mechanistic Cell Signaling, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Kondragunta V; Laboratory of Molecular and Mechanistic Cell Signaling, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Luchsinger LL; Laboratory of Stem Cell Regenerative Research, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580., Syed I; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Deaconess Medical Center and Harvard Medical School, Boston, MA 02115., Sharif H; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi 127788, United Arab Emirates., Wu H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115., Giri Magupalli V; Laboratory of Molecular and Mechanistic Cell Signaling, Lindsley F. Kimball Research Institute, New York Blood Center, Rye, NY 10580. |
| Source: | Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 12; Vol. 123 (19), pp. e2537563123. Date of Electronic Publication: 2026 May 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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