Integrated network pharmacology, transcriptomics analysis and experimental validation elucidated the underlying mechanisms of Siwu Decoction in the treatment of LPS-induced acute lung injury.
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| Title: | Integrated network pharmacology, transcriptomics analysis and experimental validation elucidated the underlying mechanisms of Siwu Decoction in the treatment of LPS-induced acute lung injury. |
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| Authors: | Lin XM; Department of Critical Care Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361015, Fujian province, PR China. Electronic address: lin.xiaoming@zsxmhospital.com., Zhang LF; Department of Critical Care Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361015, Fujian province, PR China. Electronic address: zhang.lianfang@zsxmhospital.com., Yi JL; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, 361021, Fujian province, PR China. Electronic address: m15079499029@163.com., Lin TC; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, 361021, Fujian province, PR China. Electronic address: 2677232079@qq.com., Xie RC; Department of Critical Care Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361015, Fujian province, PR China. Electronic address: xie.rongcheng@zsxmhospital.com., Tu SW; Department of Critical Care Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361015, Fujian province, PR China. Electronic address: tu.shengwen@zsxmhospital.com., Yi LT; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, 361021, Fujian province, PR China. Electronic address: litaoyi@hqu.edu.cn., Ma JF; Department of Critical Care Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361015, Fujian province, PR China; Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, PR China. Electronic address: ma.jiefei@zs-hospital.sh.cn. |
| Source: | Journal of ethnopharmacology [J Ethnopharmacol] 2026 Sep 15; Vol. 368, pp. 121827. Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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