DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX.

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Title: DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX.
Authors: Cai Y; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA., Kunkle DE; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Edinbugh MD; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Biology, Fisk University, Nashville, TN, 37208, USA., Bradley NP; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA.; AbbVie, North Chicago, IL, 60064, USA., Skaar EP; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA. eric.skaar@vumc.org.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. eric.skaar@vumc.org.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. eric.skaar@vumc.org., Eichman BF; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA. brandt.eichman@vanderbilt.edu.; Department of Biochemistry, Vanderbilt University, Nashville, TN, 37232, USA. brandt.eichman@vanderbilt.edu.
Source: EMBO reports [EMBO Rep] 2026 Jun; Vol. 27 (12), pp. 3173-3188. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cai+Y%22">Cai Y</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Kunkle+DE%22">Kunkle DE</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Edinbugh+MD%22">Edinbugh MD</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Biology, Fisk University, Nashville, TN, 37208, USA.<br /><searchLink fieldCode="AU" term="%22Bradley+NP%22">Bradley NP</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA.; AbbVie, North Chicago, IL, 60064, USA.<br /><searchLink fieldCode="AU" term="%22Skaar+EP%22">Skaar EP</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA. eric.skaar@vumc.org.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. eric.skaar@vumc.org.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. eric.skaar@vumc.org.<br /><searchLink fieldCode="AU" term="%22Eichman+BF%22">Eichman BF</searchLink>; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA. brandt.eichman@vanderbilt.edu.; Department of Biochemistry, Vanderbilt University, Nashville, TN, 37232, USA. brandt.eichman@vanderbilt.edu.
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        Value: 10.1038/s44319-026-00785-6
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      – TitleFull: DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX.
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              Text: 2026 Jun
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