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A novel Chimeric Antigen Receptor (CAR) - strategy to target EGFRVIII-mutated glioblastoma cells via macrophages.

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Title: A novel Chimeric Antigen Receptor (CAR) - strategy to target EGFRVIII-mutated glioblastoma cells via macrophages.
Authors: Vera K; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France., Esken G; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France., Hwang JW; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France., Elbaz C; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France., Chaker D; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France., Oudrhiri N; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; APHP Paris Saclay, Department of Hematology, Hospital Bicêtre and Paul Brousse, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France., Desterke C; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France., Griscelli F; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Department of Biology and Pathology, Gustave Roussy Cancer Center, Villejuif, 94000, France.; INGESTEM National iPSC Infrastructure, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France., Bennaceur-Griscelli A; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France.; APHP Paris Saclay, Department of Hematology, Hospital Bicêtre and Paul Brousse, Villejuif, 94800, France.; INGESTEM National iPSC Infrastructure, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France., Turhan AG; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France. turviv33@gmail.com.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France. turviv33@gmail.com.; APHP Paris Saclay, Department of Hematology, Hospital Bicêtre and Paul Brousse, Villejuif, 94800, France. turviv33@gmail.com.; INGESTEM National iPSC Infrastructure, Villejuif, 94800, France. turviv33@gmail.com.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France. turviv33@gmail.com.
Source: BMC cancer [BMC Cancer] 2026 May 08; Vol. 26 (1). Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel Chimeric Antigen Receptor (CAR) - strategy to target EGFR<superscript>VIII</superscript>-mutated glioblastoma cells via macrophages.
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  Data: <searchLink fieldCode="AU" term="%22Vera+K%22">Vera K</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.<br /><searchLink fieldCode="AU" term="%22Esken+G%22">Esken G</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.<br /><searchLink fieldCode="AU" term="%22Hwang+JW%22">Hwang JW</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France.<br /><searchLink fieldCode="AU" term="%22Elbaz+C%22">Elbaz C</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France.<br /><searchLink fieldCode="AU" term="%22Chaker+D%22">Chaker D</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France.<br /><searchLink fieldCode="AU" term="%22Oudrhiri+N%22">Oudrhiri N</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; APHP Paris Saclay, Department of Hematology, Hospital Bicêtre and Paul Brousse, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France.<br /><searchLink fieldCode="AU" term="%22Desterke+C%22">Desterke C</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France.<br /><searchLink fieldCode="AU" term="%22Griscelli+F%22">Griscelli F</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Department of Biology and Pathology, Gustave Roussy Cancer Center, Villejuif, 94000, France.; INGESTEM National iPSC Infrastructure, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France.<br /><searchLink fieldCode="AU" term="%22Bennaceur-Griscelli+A%22">Bennaceur-Griscelli A</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France.; APHP Paris Saclay, Department of Hematology, Hospital Bicêtre and Paul Brousse, Villejuif, 94800, France.; INGESTEM National iPSC Infrastructure, Villejuif, 94800, France.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France.<br /><searchLink fieldCode="AU" term="%22Turhan+AG%22">Turhan AG</searchLink>; INSERM UMR-S-1310, Paris Saclay University, Villejuif, 94800, France. turviv33@gmail.com.; Faculty of Medicine Paris Saclay, Paris Saclay University, Le Kremlin Bicêtre, 94270, France. turviv33@gmail.com.; APHP Paris Saclay, Department of Hematology, Hospital Bicêtre and Paul Brousse, Villejuif, 94800, France. turviv33@gmail.com.; INGESTEM National iPSC Infrastructure, Villejuif, 94800, France. turviv33@gmail.com.; CITHERA, Centre for IPSC Therapies, INSERM UMS-45, Genopole Campus, Evry, 91100, France. turviv33@gmail.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12885-026-16080-5
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        Text: English
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      – TitleFull: A novel Chimeric Antigen Receptor (CAR) - strategy to target EGFRVIII-mutated glioblastoma cells via macrophages.
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              Text: 2026 May 08
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