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Effect of antibiotic therapy versus no antibiotics on nonoperative management outcomes in uncomplicated appendicitis: A systematic review and meta-analysis.

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Title: Effect of antibiotic therapy versus no antibiotics on nonoperative management outcomes in uncomplicated appendicitis: A systematic review and meta-analysis.
Authors: Lin WT; Department of Emergency Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan., Huang YN; Department of Anesthesiology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan., Wang JH; Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan., Lin YK; Department of Emergency Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan. yklin1129@gmail.com.
Source: International journal of colorectal disease [Int J Colorectal Dis] 2026 May 09; Vol. 41 (1). Date of Electronic Publication: 2026 May 09.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Comparative Study; Review
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8607899 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1262 (Electronic) Linking ISSN: 01791958 NLM ISO Abbreviation: Int J Colorectal Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of antibiotic therapy versus no antibiotics on nonoperative management outcomes in uncomplicated appendicitis: A systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Lin+WT%22">Lin WT</searchLink>; Department of Emergency Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YN%22">Huang YN</searchLink>; Department of Anesthesiology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+JH%22">Wang JH</searchLink>; Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YK%22">Lin YK</searchLink>; Department of Emergency Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, No. 707, Sec. 3, Zhongyang Rd., Hualien City, Hualien County, 970473, Taiwan. yklin1129@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%228607899%22">International journal of colorectal disease</searchLink> [Int J Colorectal Dis] 2026 May 09; Vol. 41 (1). <i>Date of Electronic Publication: </i>2026 May 09.
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  Data: Journal Article; Systematic Review; Meta-Analysis; Comparative Study; Review
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8607899 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1262 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201791958%22">01791958 </searchLink><i>NLM ISO Abbreviation: </i>Int J Colorectal Dis <i>Subsets: </i>MEDLINE
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    Identifiers:
      – Type: doi
        Value: 10.1007/s00384-026-05147-1
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      – Code: eng
        Text: English
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      – TitleFull: Effect of antibiotic therapy versus no antibiotics on nonoperative management outcomes in uncomplicated appendicitis: A systematic review and meta-analysis.
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            NameFull: Huang YN
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            NameFull: Wang JH
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            – D: 09
              M: 05
              Text: 2026 May 09
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              Y: 2026
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              Value: 41
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            – TitleFull: International journal of colorectal disease
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