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Comparative Effectiveness and Safety of Tofacitinib, Filgotinib, and Upadacitinib in Ulcerative Colitis: A Multicenter Real-World Cohort Study.

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Title: Comparative Effectiveness and Safety of Tofacitinib, Filgotinib, and Upadacitinib in Ulcerative Colitis: A Multicenter Real-World Cohort Study.
Authors: Tursi A; Territorial Gastroenterology Service, ASL BAT, Andria, Italy.; Department of Medical and Surgical Sciences, School of Medicine, Catholic University, Rome, Italy., Pasta A; Department of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS 'San Martino'' Hospital, University of Genoa, Genoa, Italy., Elisei W; Division of Gastroenterology, A.O. 'S. Camillo-Forlanini', Rome, Italy., Barberio B; Gastroenterology Unit, Azienda Ospedale-Università Di Padova (AOUP), Padua, Italy., Mocci G; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Savarino EV; Gastroenterology Unit, Azienda Ospedale-Università Di Padova (AOUP), Padua, Italy., de Barba C; Gastroenterology Unit, Azienda Ospedale-Università Di Padova (AOUP), Padua, Italy., Maconi G; Gastroenterology Unit, Department Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Cataletti G; Gastroenterology Unit, Department Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Scaldaferri F; Digestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS Largo Francesco Vito, 1, 00168, Rome, Italy.; School of Medicine, Catholic University, Rome, Italy., Napolitano D; Digestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS Largo Francesco Vito, 1, 00168, Rome, Italy., Costa F; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy., Ceccarelli L; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy., Marzo M; Division of Gastroenterology, 'Veris-Delli Ponti' Hospital, Scorrano, LE, Italy., Monterubbianesi R; Division of Gastroenterology, A.O. 'S. Camillo-Forlanini', Rome, Italy., di Fonzo M; Division of Gastroenterology, A.O. 'S. Camillo-Forlanini', Rome, Italy., Lombardi G; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy., Patturelli M; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy., Ribaldone DG; Department of Medical Sciences, Division of Gastroenterology, IBD Unit, 'A.O.U. Citta Della Salute e Della Scienza Di Torino'', University of Turin, Turin, Italy., Bertani L; Division of Gastroenterology, 'Felice Lotti' Hospital, Azienda USL Toscana Nord Ovest, Pontedera, PI, Italy., Rodino' S; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy., Sebkova L; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy., Bodini G; Department of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS 'San Martino'' Hospital, University of Genoa, Genoa, Italy., Pranzo G; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca, TA, Italy., Serio M; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy., Scarcelli A; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy., Luppino I; Division of Gastroenterology, 'Annunziata' Hospital, Cosenza, Italy., Ferronato A; Digestive Endoscopy Unit, ULSS7 Pedemontana, Santorso, VI, Italy., Spagnuolo R; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Luzza F; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Morano D; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Gravina AG; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli'', Naples, Italy., Pellegrino R; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli'', Naples, Italy., Vespere G; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Sedda S; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Allegretta L; Division of Gastroenterology, 'Santa Caterina Novella' Hospital, Galatina (LE), Italy., Fanigliulo L; Division of Gastroenterology, 'S.S. Annunziata' Hospital, Taranto, Italy., Grossi L; Gastroenterology Unit, 'Spirito Santo' Hospital, 'G d'Annunzio' University, Pescara, Italy., Cortellini F; Division of Gastroenterology, 'Infermi' Hospital, Rimini, Italy., Forti G; Division of Digestive Endoscopy, 'S. Maria Goretti' Hospital, Latina, Italy., Neve V; Division of Gastroenterology, 'A. Perrino' Hospital, Brindisi, Italy., Piergallini S; Division of Gastroenterology, IBD Unit, 'A. Murri' Hospital, Fermo, Italy., Scarozza P; Division of Gastroenterology, 'Ospedale Dei Castelli', Ariccia, Rome, Italy., Bevevino G; Division of Gastroenterology, 'Ospedale Dei Castelli', Ariccia, Rome, Italy., Iacopini F; Division of Gastroenterology, 'Ospedale Dei Castelli', Ariccia, Rome, Italy., Capone P; Division of Gastroenterology, 'T. Maresca' Hospital, Torre del Greco, NA, Italy., Gaiani F; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy., Kayali S; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy., Mucherino C; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna E S. Sebastiano', Caserta, Italy., D'antonio E; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna E S. Sebastiano', Caserta, Italy., D'ascoli B; Division of Gastroenterology, 'Madonna Delle Grazie' Hospital, Matera, Italy., Colucci R; Digestive Endoscopy Unit, 'San Matteo Degli Infermi' Hospital, Spoleto, PG, Italy., Bachetti F; Digestive Endoscopy Unit, 'San Matteo Degli Infermi' Hospital, Spoleto, PG, Italy., Giorgetti GM; Clinical Nutrition and Digestive Endoscopy Unit, 'S. Eugenio' Hospital, Rome, Italy., Clemente V; Clinical Nutrition and Digestive Endoscopy Unit, 'S. Eugenio' Hospital, Rome, Italy., Pagnini C; Division of Gastroenterology, 'S. Giovanni-Addolorata' Hospital, Rome, Italy., Cuomo A; Division of Gastroenterology, Umberto I' Hospital, Nocera Inferiore, SA, Italy., Donnarumma L; Division of Gastroenterology, Umberto I' Hospital, Nocera Inferiore, SA, Italy., Onidi FM; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Satta PU; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Picchio M; Division of General Surgery, 'P. Colombo' Hospital, ASL Roma 6, Velletri, Rome, Italy., Papa A; Digestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS Largo Francesco Vito, 1, 00168, Rome, Italy. alfredo.papa@unicatt.it.; School of Medicine, Catholic University, Rome, Italy. alfredo.papa@unicatt.it.
Corporate Authors: Italian Network for Inflammatory Bowel Diseases (IN-IBD)
Source: Advances in therapy [Adv Ther] 2026 Jul; Vol. 43 (7), pp. 3165-3186. Date of Electronic Publication: 2026 May 09.
Publication Type: Journal Article; Multicenter Study; Comparative Study
Journal Info: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparative Effectiveness and Safety of Tofacitinib, Filgotinib, and Upadacitinib in Ulcerative Colitis: A Multicenter Real-World Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Tursi+A%22">Tursi A</searchLink>; Territorial Gastroenterology Service, ASL BAT, Andria, Italy.; Department of Medical and Surgical Sciences, School of Medicine, Catholic University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pasta+A%22">Pasta A</searchLink>; Department of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS 'San Martino'' Hospital, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Elisei+W%22">Elisei W</searchLink>; Division of Gastroenterology, A.O. 'S. 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  Data: <searchLink fieldCode="JN" term="%228611864%22">Advances in therapy</searchLink> [Adv Ther] 2026 Jul; Vol. 43 (7), pp. 3165-3186. <i>Date of Electronic Publication: </i>2026 May 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Health+Communications+Inc%22">Health Communications Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8611864 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1865-8652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220741238X%22">0741238X </searchLink><i>NLM ISO Abbreviation: </i>Adv Ther <i>Subsets: </i>MEDLINE
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      – TitleFull: Comparative Effectiveness and Safety of Tofacitinib, Filgotinib, and Upadacitinib in Ulcerative Colitis: A Multicenter Real-World Cohort Study.
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            NameFull: Gravina AG
      – PersonEntity:
          Name:
            NameFull: Pellegrino R
      – PersonEntity:
          Name:
            NameFull: Vespere G
      – PersonEntity:
          Name:
            NameFull: Sedda S
      – PersonEntity:
          Name:
            NameFull: Allegretta L
      – PersonEntity:
          Name:
            NameFull: Fanigliulo L
      – PersonEntity:
          Name:
            NameFull: Grossi L
      – PersonEntity:
          Name:
            NameFull: Cortellini F
      – PersonEntity:
          Name:
            NameFull: Forti G
      – PersonEntity:
          Name:
            NameFull: Neve V
      – PersonEntity:
          Name:
            NameFull: Piergallini S
      – PersonEntity:
          Name:
            NameFull: Scarozza P
      – PersonEntity:
          Name:
            NameFull: Bevevino G
      – PersonEntity:
          Name:
            NameFull: Iacopini F
      – PersonEntity:
          Name:
            NameFull: Capone P
      – PersonEntity:
          Name:
            NameFull: Gaiani F
      – PersonEntity:
          Name:
            NameFull: Kayali S
      – PersonEntity:
          Name:
            NameFull: Mucherino C
      – PersonEntity:
          Name:
            NameFull: D'antonio E
      – PersonEntity:
          Name:
            NameFull: D'ascoli B
      – PersonEntity:
          Name:
            NameFull: Colucci R
      – PersonEntity:
          Name:
            NameFull: Bachetti F
      – PersonEntity:
          Name:
            NameFull: Giorgetti GM
      – PersonEntity:
          Name:
            NameFull: Clemente V
      – PersonEntity:
          Name:
            NameFull: Pagnini C
      – PersonEntity:
          Name:
            NameFull: Cuomo A
      – PersonEntity:
          Name:
            NameFull: Donnarumma L
      – PersonEntity:
          Name:
            NameFull: Onidi FM
      – PersonEntity:
          Name:
            NameFull: Satta PU
      – PersonEntity:
          Name:
            NameFull: Picchio M
      – PersonEntity:
          Name:
            NameFull: Papa A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1865-8652
          Numbering:
            – Type: volume
              Value: 43
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Advances in therapy
              Type: main
ResultId 1