Pharmacological blockade of CRHR1 prevents early-onset puberty and enhanced anxiety-like behavior induced by early-life adversity in female Sprague Dawley rats.

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Title: Pharmacological blockade of CRHR1 prevents early-onset puberty and enhanced anxiety-like behavior induced by early-life adversity in female Sprague Dawley rats.
Authors: Balakrishnan A; Department of Psychology, Northeastern University, Boston, MA, United States of America., Roy S; Department of Psychology, Northeastern University, Boston, MA, United States of America., Lin V; Department of Psychology, Northeastern University, Boston, MA, United States of America., Thakur P; Department of Psychology, Northeastern University, Boston, MA, United States of America., Brenhouse HC; Department of Psychology, Northeastern University, Boston, MA, United States of America. Electronic address: h.brenhouse@northeastern.edu.
Source: Hormones and behavior [Horm Behav] 2026 Jun; Vol. 182, pp. 105936. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0217764 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6867 (Electronic) Linking ISSN: 0018506X NLM ISO Abbreviation: Horm Behav Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-6867
DOI:10.1016/j.yhbeh.2026.105936