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Pharmacological blockade of CRHR1 prevents early-onset puberty and enhanced anxiety-like behavior induced by early-life adversity in female Sprague Dawley rats.

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Title: Pharmacological blockade of CRHR1 prevents early-onset puberty and enhanced anxiety-like behavior induced by early-life adversity in female Sprague Dawley rats.
Authors: Balakrishnan A; Department of Psychology, Northeastern University, Boston, MA, United States of America., Roy S; Department of Psychology, Northeastern University, Boston, MA, United States of America., Lin V; Department of Psychology, Northeastern University, Boston, MA, United States of America., Thakur P; Department of Psychology, Northeastern University, Boston, MA, United States of America., Brenhouse HC; Department of Psychology, Northeastern University, Boston, MA, United States of America. Electronic address: h.brenhouse@northeastern.edu.
Source: Hormones and behavior [Horm Behav] 2026 Jun; Vol. 182, pp. 105936. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0217764 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6867 (Electronic) Linking ISSN: 0018506X NLM ISO Abbreviation: Horm Behav Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Balakrishnan+A%22">Balakrishnan A</searchLink>; Department of Psychology, Northeastern University, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Roy+S%22">Roy S</searchLink>; Department of Psychology, Northeastern University, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Lin+V%22">Lin V</searchLink>; Department of Psychology, Northeastern University, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Thakur+P%22">Thakur P</searchLink>; Department of Psychology, Northeastern University, Boston, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Brenhouse+HC%22">Brenhouse HC</searchLink>; Department of Psychology, Northeastern University, Boston, MA, United States of America. Electronic address: h.brenhouse@northeastern.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0217764 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-6867 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220018506X%22">0018506X </searchLink><i>NLM ISO Abbreviation: </i>Horm Behav <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.yhbeh.2026.105936
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      – Code: eng
        Text: English
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      – TitleFull: Pharmacological blockade of CRHR1 prevents early-onset puberty and enhanced anxiety-like behavior induced by early-life adversity in female Sprague Dawley rats.
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              Text: 2026 Jun
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