Targeted Nrf2 activation improves vascular endothelial function with aging and prevents vascular dysfunction following disuse in younger and older adults.
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| Title: | Targeted Nrf2 activation improves vascular endothelial function with aging and prevents vascular dysfunction following disuse in younger and older adults. |
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| Authors: | Carlini NA; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Hanson BE; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Ruple BA; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Craig JC; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Fermoyle CC; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Faculty of Medicine and Health, University of Sydney, Australia., McKenzie AI; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Bisconti AV; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Pelka EZ; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Supiano MA; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States., Tuday E; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Division of Cardiology, Department of Internal Medicine, The University of Utah School of Medicine, Salt Lake City, UT, United States., Richardson RS; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, United States., Drummond MJ; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, United States; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, UT, United States; Molecular Medicine Program, University of Utah, Salt Lake City, UT, United States., Rajasekaran NS; Cardiac Aging and Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, United States., Broxterman RM; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States., Trinity JD; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, United States. Electronic address: joel.trinity@hscutah.edu. |
| Source: | Free radical biology & medicine [Free Radic Biol Med] 2026 May 07; Vol. 254, pp. 827-841. Date of Electronic Publication: 2026 May 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42105792 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Targeted Nrf2 activation improves vascular endothelial function with aging and prevents vascular dysfunction following disuse in younger and older adults. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Carlini+NA%22">Carlini NA</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Hanson+BE%22">Hanson BE</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Ruple+BA%22">Ruple BA</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Craig+JC%22">Craig JC</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Fermoyle+CC%22">Fermoyle CC</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Faculty of Medicine and Health, University of Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22McKenzie+AI%22">McKenzie AI</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Bisconti+AV%22">Bisconti AV</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Pelka+EZ%22">Pelka EZ</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Supiano+MA%22">Supiano MA</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Tuday+E%22">Tuday E</searchLink>; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Division of Cardiology, Department of Internal Medicine, The University of Utah School of Medicine, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Richardson+RS%22">Richardson RS</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Drummond+MJ%22">Drummond MJ</searchLink>; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, United States; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, UT, United States; Molecular Medicine Program, University of Utah, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Rajasekaran+NS%22">Rajasekaran NS</searchLink>; Cardiac Aging and Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Broxterman+RM%22">Broxterman RM</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States.<br /><searchLink fieldCode="AU" term="%22Trinity+JD%22">Trinity JD</searchLink>; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, United States; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, United States; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, United States. Electronic address: joel.trinity@hscutah.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228709159%22">Free radical biology & medicine</searchLink> [Free Radic Biol Med] 2026 May 07; Vol. 254, pp. 827-841. <i>Date of Electronic Publication: </i>2026 May 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8709159 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208915849%22">08915849 </searchLink><i>NLM ISO Abbreviation: </i>Free Radic Biol Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42105792 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.freeradbiomed.2026.05.282 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 827 Titles: – TitleFull: Targeted Nrf2 activation improves vascular endothelial function with aging and prevents vascular dysfunction following disuse in younger and older adults. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Carlini NA – PersonEntity: Name: NameFull: Hanson BE – PersonEntity: Name: NameFull: Ruple BA – PersonEntity: Name: NameFull: Craig JC – PersonEntity: Name: NameFull: Fermoyle CC – PersonEntity: Name: NameFull: McKenzie AI – PersonEntity: Name: NameFull: Bisconti AV – PersonEntity: Name: NameFull: Pelka EZ – PersonEntity: Name: NameFull: Supiano MA – PersonEntity: Name: NameFull: Tuday E – PersonEntity: Name: NameFull: Richardson RS – PersonEntity: Name: NameFull: Drummond MJ – PersonEntity: Name: NameFull: Rajasekaran NS – PersonEntity: Name: NameFull: Broxterman RM – PersonEntity: Name: NameFull: Trinity JD IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 05 Text: 2026 May 07 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1873-4596 Numbering: – Type: volume Value: 254 Titles: – TitleFull: Free radical biology & medicine Type: main |
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